ID M3XJZ5_LATCH Unreviewed; 557 AA.
AC M3XJZ5;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Glycoprotein nmb {ECO:0000313|Ensembl:ENSLACP00000023051.1};
GN Name=GPNMB {ECO:0000313|Ensembl:ENSLACP00000023051.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000023051.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000023051.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PMEL/NMB family.
CC {ECO:0000256|ARBA:ARBA00025776}.
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DR EMBL; AFYH01080484; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01080485; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01080486; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01080487; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3XJZ5; -.
DR Ensembl; ENSLACT00000026697.1; ENSLACP00000023051.1; ENSLACG00000012475.2.
DR GeneTree; ENSGT00950000183188; -.
DR HOGENOM; CLU_017264_1_0_1; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000012475; Expressed in pectoral fin and 1 other cell type or tissue.
DR CDD; cd00146; PKD; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR045219; PKAT.
DR InterPro; IPR046846; PKAT_KLD.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR11861; MELANOCYTE PROTEIN PMEL 17-RELATED; 1.
DR PANTHER; PTHR11861:SF11; TRANSMEMBRANE GLYCOPROTEIN NMB; 1.
DR Pfam; PF20433; PKAT_KLD; 1.
DR Pfam; PF00801; PKD; 1.
DR SMART; SM00089; PKD; 1.
DR SUPFAM; SSF49299; PKD domain; 1.
DR PROSITE; PS50093; PKD; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 297..334
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT REGION 352..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 557 AA; 62310 MW; 46557092583C9F9F CRC64;
MLFCQGSYLF QTMKWASFLC CLGLTLMLSG VETHKSFRDA MPSGRSQLLA RSHVSSVRNH
QTLQGWQSDN NTWNENLYPI WKTNDSKWKN YWRGGKVIAH LTSDSPALVG SNVTFSVTLQ
FPRCQKENKN GDLVYDDNCK SDSSVFPGEF VYNWTSWLEQ YGWGVCSNIL RCNVFPDGKP
FPFHHDWRRR NFVFVFHTLG QYYQKTSSSS ATISLNTMNI TLGTHLMEVA VYHKRRYRNY
IPVATVTTLF DVTDKIPFFV QISQKNDVNI FDKVFIKDLK VIFDVRIHDP SNYLKNSNVS
YKWDFGDSRR LASNSSVVTH TYTRVGKFHP QLTIRAIIPV PCGPVTQTPF PFTSESTTAS
ATTTEQMTSQ TTRDPTTMTS QTTPFTVTPS LPTTFAIKTS TRTAIPTSAA TETSTETKTS
LPTARFPQPA GCQLYRYGQY NTSLIIVEGI TSVSIVQVTS VVEVSASQVT NAIMEFVVTC
QGGIPTDVCT IILDFSCTTT KDVFCDSVPP ADKCQLTLQR AFNQTEPFCV NITLSDGGSL
AATSTLVSIG KGGFLNW
//
