ID M3XQJ1_MUSPF Unreviewed; 1987 AA.
AC M3XQJ1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE SubName: Full=Minichromosome maintenance complex component 3 associated protein {ECO:0000313|Ensembl:ENSMPUP00000001341.1};
GN Name=MCM3AP {ECO:0000313|Ensembl:ENSMPUP00000001341.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000001341.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000001341.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SAC3 family.
CC {ECO:0000256|ARBA:ARBA00038443}.
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DR EMBL; AEYP01099700; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01099701; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004780327.1; XM_004780270.2.
DR STRING; 9669.ENSMPUP00000001341; -.
DR Ensembl; ENSMPUT00000001369.1; ENSMPUP00000001341.1; ENSMPUG00000001353.1.
DR KEGG; mpuf:101689042; -.
DR eggNOG; KOG1860; Eukaryota.
DR GeneTree; ENSGT00940000156322; -.
DR HOGENOM; CLU_001842_1_0_1; -.
DR InParanoid; M3XQJ1; -.
DR OMA; DMTIFWH; -.
DR OrthoDB; 91913at2759; -.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0031965; C:nuclear membrane; IEA:Ensembl.
DR GO; GO:0044615; C:nuclear pore nuclear basket; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0070390; C:transcription export complex 2; IEA:Ensembl.
DR GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR GO; GO:0042393; F:histone binding; IEA:Ensembl.
DR GO; GO:0010484; F:histone H3 acetyltransferase activity; IEA:Ensembl.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0034728; P:nucleosome organization; IEA:Ensembl.
DR GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IEA:Ensembl.
DR GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; IEA:Ensembl.
DR CDD; cd12443; RRM_MCM3A_like; 1.
DR Gene3D; 1.25.40.990; -; 1.
DR Gene3D; 6.10.250.1340; -; 1.
DR InterPro; IPR031910; GANP_CID_dom.
DR InterPro; IPR031907; MCM3AP_GANP.
DR InterPro; IPR034265; MCM3AP_RRM.
DR InterPro; IPR031908; NupH_GANP.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR045107; SAC3/GANP/THP3.
DR InterPro; IPR005062; SAC3/GANP/THP3_conserved.
DR PANTHER; PTHR12436; 80 KDA MCM3-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR12436:SF3; GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN; 1.
DR Pfam; PF16766; CID_GANP; 1.
DR Pfam; PF16769; MCM3AP_GANP; 1.
DR Pfam; PF16768; NupH_GANP; 1.
DR Pfam; PF03399; SAC3_GANP; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 775..958
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 237..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 511..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1060..1081
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1140..1171
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 36..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..255
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..330
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..369
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..414
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..526
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1060..1080
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1987 AA; 218427 MW; 88A0A17273ED268B CRC64;
MNPAAPFSGP QPGVFPAATS SSVGTFQAKP PFRFGQPSSF GQNNTLSGKT SGFSQVSSFP
TSSGLSHSSP AQTLGFSQTS NVGLFSGLEQ TPAFVAASGS SSSCVSAHPG FSFKSPNFGA
FPGTSSFGQE SGEIASSAFG KTEFSFKPLE NSVFRPIFGA ESEPEKTQSS VTSGFFTFSH
PISSGPGGLA PFSFPQVTSS SAATSNFTFS KPVNSNNSSS AFTSALSNQN VEEEKRASKS
LFGSSNSSFT NFPVSSGPLG EPFPGSKTGV RQGCEERVSQ MEPLPSLTKG LKRKEDQDRS
PRRPGHDAAE DVDALSRGDH PPDKRPVRLN RPRGGTLFGR TIQDVFKSNK EVSRLGNKES
KKDIGCAESG ENDHVAIPGG SPSVLAPSRL PGVNKEEETE SREKKEDSLR GTPGRQSKRS
ESTDSLGGLS ATEITAIQCK NIPDSLNNRT ILENHFGKIA KVQRIYTRRS KKLAVVYFFD
HVSAALARKK GKGLHKDMSI FWHKKKISPN KKPFSIKEKK PGDGEAGQGP EDTAFQHSSL
GKPGARAAAG SLLNKSSPVK KPSLLKTHQF EGDPFDSGSE GSEGLGPCVS SLSTLIGTVA
ETSEEKYRLL DQRDRIMRQA RVKRTDLDKA RTFVGTCPDM CPEKERYMRE TRSQLSVFEV
VPGTDQVDHA AAVKEYSRSS ADQEEPLPHE LRPSAVLSRT MDYLVTQIMD QKEGSLRDWY
DFVWNRTRGI RKDITQQHLC DPVTVSLIEK CTRFHIHCAH FLCEEPMSSF DAKINNENMT
KCLQSLKEMY QDLRNKGVCC AGEAEFQGYN VLLSLNKGDI LREVQQFHPT VRNSSEVKFA
VQAFAALNSN NFVRFFKLVR SASYLNACLL HCYFNQIRKD ALRALNIAYT VSTQRSTVFP
LDSVVRMLLF QDGEEATDFL NFYGLTVSDG CVELNRSSFL EPEGLSKARK SVFITRKLTV
SVGEIVNGGP LPPVPRHTPV CSFNSQNKYI GESLAAELPV GTQRPSLDTV GGAKGEACGA
EAEVPPTTLL QQPLPSAAPT PASLPHVPAP TPSIVPGLFQ PPGQPPIQPP AQPELLPPRP
APSYSDADLA QVVDELIQEV LQRDCEEVGA AGAAFATTAL GVSNAAMEEL LTAATAGILR
RVAVEEVAKE RERREEERRQ AEERLKQERE LVLTQLSQGL ATELTELVVT ECVRETCSQE
LKSAVETDQQ VRMARCCEDV CAHLVDWFLG EEIFQTAKET LQELQCFCKY LQRWREAVAA
RKKLRRQMRA FPAAPCCVDM NDRLRALVPS AECPIARENL AKGLLDLGHA GKVGISCTRL
RWLRNKTAHQ MKVQHFYKQL LSDAAWVPLD LPSLVAEHLP GRRERVFWKL VLVLPDGEEQ
SPGNPGRILA NWLQVKFMGR DGSVGDTNSE AGGIQTLALF HALSSKGDRT VAVNVCIKVV
HGALSDYALD AVETQKELLG ASGLMLLLPP KVESEDVAEE DVYWLSALLQ LKQLLQAKPF
QPALPLVVLV PSPAGHAMEK EVEDGLMLRD LVSAKLISDY TVIAIPDSIN DLQGTTKVSR
AVQWLVSHCP CSLDLCCQTL IQYVEDGVGR EFSGRFFRDR RERRQGGLAS QEPGAIIELF
NSVLHFLASL VSSEQLCDLS WPVTEFAEAG GSQLLPHLHW NAPEHLAWLR QAVLSFQLPQ
MDFPPPGAPW LPMCSMVVQY ASQIPSSRQT QPVLQSQVEN LLCRTYRRWK SKSHSLDPGT
GPSVADLPWD DVIALCINHK LRDWTPPRLP VTAEALSEDG QICVYFFKNH LKKYDVPLSW
EQARMQTQKE LHLSQERLGI KSFHPANKFP APLLHMHRKG KRNVERSPER VVPSTQGLVC
GASAQELLAQ CLSRSLLLEK EESKRFEDQL QQWLSADSGV FTGSRSLPLY LPQTLVSLPH
TIEPVMKTVT TASPQNERTG EQLQLSEATG TSVSERLKHL ERLMQSSREE EVASELHLSA
LLDMVDI
//
