ID M3YDH4_MUSPF Unreviewed; 764 AA.
AC M3YDH4;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Nucleolar transcription factor 1 isoform X1 {ECO:0000313|RefSeq:XP_044936710.1, ECO:0000313|RefSeq:XP_044936711.1};
DE SubName: Full=Upstream binding transcription factor {ECO:0000313|Ensembl:ENSMPUP00000009381.1};
GN Name=UBTF {ECO:0000313|Ensembl:ENSMPUP00000009381.1,
GN ECO:0000313|RefSeq:XP_044936710.1, ECO:0000313|RefSeq:XP_044936711.1,
GN ECO:0000313|RefSeq:XP_044936712.1, ECO:0000313|RefSeq:XP_044936713.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000009381.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000009381.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_044936710.1, ECO:0000313|RefSeq:XP_044936711.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_044936710.1,
RC ECO:0000313|RefSeq:XP_044936711.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AEYP01079354; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004772601.1; XM_004772544.2.
DR RefSeq; XP_044936710.1; XM_045080775.1.
DR RefSeq; XP_044936711.1; XM_045080776.1.
DR RefSeq; XP_044936712.1; XM_045080777.1.
DR RefSeq; XP_044936713.1; XM_045080778.1.
DR STRING; 9669.ENSMPUP00000009381; -.
DR Ensembl; ENSMPUT00000009535.1; ENSMPUP00000009381.1; ENSMPUG00000009456.1.
DR KEGG; mpuf:101680939; -.
DR eggNOG; KOG0381; Eukaryota.
DR GeneTree; ENSGT00940000161141; -.
DR HOGENOM; CLU_021068_1_0_1; -.
DR OMA; RTAYKEY; -.
DR OrthoDB; 4260911at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0001650; C:fibrillar center; IEA:Ensembl.
DR GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR GO; GO:0001165; F:RNA polymerase I cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0001164; F:RNA polymerase I core promoter sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0001181; F:RNA polymerase I general transcription initiation factor activity; IEA:Ensembl.
DR GO; GO:0097110; F:scaffold protein binding; IEA:Ensembl.
DR CDD; cd21998; HMG-box_UBF1_rpt1-like; 1.
DR CDD; cd21999; HMG-box_UBF1_rpt2; 1.
DR CDD; cd22000; HMG-box_UBF1_rpt3; 1.
DR CDD; cd22001; HMG-box_UBF1_rpt4; 1.
DR CDD; cd22002; HMG-box_UBF1_rpt5; 1.
DR CDD; cd22003; HMG-box_UBF1_rpt6-like; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 6.
DR InterPro; IPR029215; HMG_box_5.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR46318:SF4; NUCLEOLAR TRANSCRIPTION FACTOR 1; 1.
DR PANTHER; PTHR46318; UPSTREAM BINDING TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00505; HMG_box; 3.
DR Pfam; PF09011; HMG_box_2; 1.
DR Pfam; PF14887; HMG_box_5; 1.
DR SMART; SM00398; HMG; 6.
DR SUPFAM; SSF47095; HMG-box; 6.
DR PROSITE; PS50118; HMG_BOX_2; 6.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Reference proteome {ECO:0000313|Proteomes:UP000000715};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 112..180
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 196..264
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 298..362
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 407..475
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 482..549
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 568..634
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 112..180
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 196..264
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 298..362
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 407..475
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 482..549
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 568..634
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 457..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 546..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 648..764
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..671
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 676..746
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 747..764
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 764 AA; 89335 MW; ACA3ACEFDBA918DE CRC64;
MNGEADCPTD LEMAAPKGQD RWSQEDMLTL LECMKNNLPS NDSSKFKTTE SHMDWEKVAF
KDFSGDMCKL KWVEISNEVR KFRTLTELIL DAQEHVKNPY KGKKLKKHPD FPKKPLTPYF
RFFMEKRAKY AKLHPEMSNL DLTKILSKKY KELPEKKKMK YIQDFQREKQ EFERNLARFR
EDHPDLIQNA KKSDIPEKPK TPQQLWYTHE KKVYLKVRPD ATTKEVKDSL GKQWSQLSDK
KRLKWIHKAL EQRKEYEEIM RDYIQKHPEL NISEEGITKS TLTKAERQLK DKFDGRPTKP
PPNSYSLYCA ELMANMKDVP STERMVLCSQ QWKLLSQKEK DAYHKKCDQK KKDYEVELLR
FLESLPEEEQ QRVLGEEKML SINKKQATSP ASKKPSQEGG KGGSEKPKRP VSAMFIFSEE
KRRQLQEERP ELSESELTRL LARMWNDLSE KKKAKYKARE AALKAQSERK PGGDREERGK
LPESPKRAEE IWQQSVIGDY LARFKNDRVK ALKAMEMTWN NMEKKEKLMW IKKAAEDQKR
YERELSEMRA PPAAANSSKK MKFQGEPKKP PMNGYQKFSQ ELLSNGELNH LPLKERMVEI
GSRWQRISQS QKEHYKKLAE EQQKQYKVHL DLWVKSLSPQ DRAAYKEYIS NKRKSMTKLR
GPNPKSSRTA LQSKSESEED DEEDEEDEDE DEEEEDDENG DSSEDGGDSS ESSSEDESED
GDENEEDDED EDDDEDDDED EDNESEGSSS SSSSSGDSSD SDSN
//
