ID M3YV80_MUSPF Unreviewed; 1206 AA.
AC M3YV80;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=ATPase 13A1 {ECO:0000313|Ensembl:ENSMPUP00000015240.1};
GN Name=ATP13A1 {ECO:0000313|Ensembl:ENSMPUP00000015240.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000015240.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000015240.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type V subfamily. {ECO:0000256|ARBA:ARBA00006000}.
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DR EMBL; AEYP01051370; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004760898.1; XM_004760841.2.
DR AlphaFoldDB; M3YV80; -.
DR STRING; 9669.ENSMPUP00000015240; -.
DR Ensembl; ENSMPUT00000015479.1; ENSMPUP00000015240.1; ENSMPUG00000015350.1.
DR GeneID; 101676538; -.
DR KEGG; mpuf:101676538; -.
DR CTD; 57130; -.
DR eggNOG; KOG0209; Eukaryota.
DR GeneTree; ENSGT00550000075064; -.
DR HOGENOM; CLU_001828_4_1_1; -.
DR InParanoid; M3YV80; -.
DR OMA; QKTKYVW; -.
DR OrthoDB; 6047at2759; -.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140567; F:membrane protein dislocase activity; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0140358; F:P-type transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0140569; P:extraction of mislocalized protein from ER membrane; IEA:Ensembl.
DR CDD; cd07543; P-type_ATPase_cation; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR006544; P-type_TPase_V.
DR InterPro; IPR047820; P5A-type_ATPase.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR NCBIfam; TIGR01657; P-ATPase-V; 1.
DR PANTHER; PTHR45630; CATION-TRANSPORTING ATPASE-RELATED; 1.
DR PANTHER; PTHR45630:SF7; ENDOPLASMIC RETICULUM TRANSMEMBRANE HELIX TRANSLOCASE; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 68..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1054..1075
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1105..1123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1135..1153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1173..1193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 891..931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1206 AA; 132723 MW; 956D47B61DF2F879 CRC64;
MAAAAAAAVG NAVPCGARPC GARPGGQPKP GPQPPTLLAA GPALIASGDE LVAAVWPYRR
PALLRRLTVL PFAGLLYPAW LGAAAAGCWG WGSSWVQIPE AALLVLATIC LAHALTVLSG
HWSVHAHCAL TCTPEYDPSK ATFVKVVPTP NNGSTELVAL HRDEGEDGQE VLSFEFQKIK
YSYDALEKKR FLPVAFPVGN AFSYYQSNRG FQEDSEIRAA EKKFGSNKAE MVVPDFSELF
KERATAPFFV FQVFCVGLWC LDEYWYYSVF TLSMLVAFEA SLVQQQMRNM SEIRKMGNKP
HLIQVYRSRK WRPIASDEIV PGDIVSIGRS PQENLVPCDV LLLRGRCIVD EAMLTGESVP
QMKEPIEDLN PDRVLDLQAD SRLHVIFGGT KVVQHIPPQK ATTGLKPVDN GCVAYVLRTG
FNTSQGKLLR TILFGVKRVT ANNLETFIFI LFLLVFAIAA AAYVWIEGTK DPSRNRYKLF
LECTLILTSV VPPELPIELS LAVNTSLIAL AKLYMYCTEP FRIPFAGKVE VCCFDKTGTL
TSDSLVVRGV AGLKDGKEVT PVSNIPVETH RALASCHSLM QLDDGTLVGD PLEKAMLTAV
DWTLTKDEKV FPRSIKTQGL KIHQRFHFAS ALKRMSVLAS YEKLGSTDLC YIAAVKGAPE
TLHSMFAQCP PDYHHIHTEI SREGARVLAL GYKELGHLTH QQAREIKREA LECNLKFVGF
IVVSCPLKAD SKAVIREIQN ASHRVVMITG DNPLTACHVA QELHFIEKAQ TLILQPPTEK
GRPCEWRSID GSVVLPLAKG SPKALALEHA LCLTGDGLAH LQAEDPQQLL RLIPHVQVFA
RVAPKQKEFV ITSLKELGYV TLMCGDGTND VGALKHADVG VALLANAPER VVERRRRPRD
SPVLSSSGGR APSRAAKQRS GLPPPEEQLA SQRDRLSQVL RELEDESTPI VKLGDASIAA
PFTSKLSSIQ CICHVIKQGR CTLVTTLQMF KILALNALIL AYSQSVLYLE GVKFSDFQAT
LQGLLLAGCF LFISRSKPLK TLSRERPLPN IFNLYTVLTV VLQFCVHFLS LVYLYSEAQA
RSPEKQEQFV DLYKEFEPSL VNSTVYIMAM AMQMATFAIN YKGPPFMESL PENRPLVWSL
AVSLLAIVGL LLGSSPDFNS QFGLVDIPVE FKLVIAQVLL LDFCLALLAD RVLQFFLGTP
KLKVPS
//
