ID   M3YWP3_MUSPF            Unreviewed;       307 AA.
AC   M3YWP3;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 54.
DE   RecName: Full=palmitoyl-protein hydrolase {ECO:0000256|ARBA:ARBA00012423};
DE            EC=3.1.2.22 {ECO:0000256|ARBA:ARBA00012423};
GN   Name=LYPLA2 {ECO:0000313|Ensembl:ENSMPUP00000015753.1};
OS   Mustela putorius furo (European domestic ferret) (Mustela furo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Mustelinae; Mustela.
OX   NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000015753.1};
RN   [1] {ECO:0000313|Ensembl:ENSMPUP00000015753.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAR-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. AB hydrolase 2
CC       family. {ECO:0000256|ARBA:ARBA00006499}.
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DR   EMBL; AEYP01008239; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_004741257.1; XM_004741200.2.
DR   AlphaFoldDB; M3YWP3; -.
DR   STRING; 9669.ENSMPUP00000015753; -.
DR   MEROPS; S09.025; -.
DR   Ensembl; ENSMPUT00000015994.1; ENSMPUP00000015753.1; ENSMPUG00000015860.1.
DR   GeneID; 101676840; -.
DR   KEGG; mpuf:101676840; -.
DR   CTD; 11313; -.
DR   eggNOG; KOG2112; Eukaryota.
DR   GeneTree; ENSGT00940000156197; -.
DR   HOGENOM; CLU_049413_3_5_1; -.
DR   InParanoid; M3YWP3; -.
DR   OMA; WYDILAM; -.
DR   OrthoDB; 4670340at2759; -.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005795; C:Golgi stack; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0004622; F:lysophospholipase activity; IEA:Ensembl.
DR   GO; GO:0008474; F:palmitoyl-(protein) hydrolase activity; IEA:Ensembl.
DR   GO; GO:0046464; P:acylglycerol catabolic process; IEA:Ensembl.
DR   GO; GO:1905344; P:prostaglandin catabolic process; IEA:Ensembl.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR003140; PLipase/COase/thioEstase.
DR   PANTHER; PTHR10655:SF13; ACYL-PROTEIN THIOESTERASE 2; 1.
DR   PANTHER; PTHR10655; LYSOPHOSPHOLIPASE-RELATED; 1.
DR   Pfam; PF02230; Abhydrolase_2; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
FT   DOMAIN          89..303
FT                   /note="Phospholipase/carboxylesterase/thioesterase"
FT                   /evidence="ECO:0000259|Pfam:PF02230"
FT   REGION          38..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        47..64
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   307 AA;  33612 MW;  67661A0D8881D966 CRC64;
     MAAPIWRIAD AHFRVPYRWP GYFRQRDGWV PGTRTEVPAG AAEGEECVSV QEKEENRPRG
     LETPREWRPQ PWSLQCMCGN TMSVPLLTDA ATVSGAERET AAVIFLHGLG DTGHSWADAL
     STIRLPHVKY ICPHAPRIPV TLNMKMVMPS WFDLMGLSPD APEDEAGIKK AAENIKALIE
     HEMKNGIPAN RIVLGGFSQG GALSLYTALT CPHPLAGIVA LSCWLPLHRA FPQAANGSAK
     DLAILQCHGE LDPMVPVRFG ALTAEKLRSV VTPARVQFKT YPGVMHSSCP QEMAAVKEFL
     EKLLPPV
//