ID M3ZAK9_NOMLE Unreviewed; 933 AA.
AC M3ZAK9;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=BICD cargo adaptor 1 {ECO:0000313|Ensembl:ENSNLEP00000023746.2};
GN Name=BICD1 {ECO:0000313|Ensembl:ENSNLEP00000023746.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000023746.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000023746.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000023746.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the BicD family.
CC {ECO:0000256|ARBA:ARBA00010061}.
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DR EMBL; ADFV01103394; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01103395; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01103396; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01103397; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01103398; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01103399; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01103400; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01103401; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01103402; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01103403; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3ZAK9; -.
DR STRING; 61853.ENSNLEP00000023746; -.
DR Ensembl; ENSNLET00000032120.2; ENSNLEP00000023746.2; ENSNLEG00000016545.3.
DR GeneTree; ENSGT00940000154471; -.
DR HOGENOM; CLU_014107_0_0_1; -.
DR InParanoid; M3ZAK9; -.
DR OMA; KAEHDCE; -.
DR Proteomes; UP000001073; Chromosome 23.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0005881; C:cytoplasmic microtubule; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:Ensembl.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR GO; GO:0099503; C:secretory vesicle; IEA:Ensembl.
DR GO; GO:0005802; C:trans-Golgi network; IEA:Ensembl.
DR GO; GO:0008093; F:cytoskeletal anchor activity; IEA:Ensembl.
DR GO; GO:0034452; F:dynactin binding; IEA:Ensembl.
DR GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:Ensembl.
DR GO; GO:0019901; F:protein kinase binding; IEA:Ensembl.
DR GO; GO:0031267; F:small GTPase binding; IEA:Ensembl.
DR GO; GO:0072385; P:minus-end-directed organelle transport along microtubule; IEA:Ensembl.
DR GO; GO:1904781; P:positive regulation of protein localization to centrosome; IEA:Ensembl.
DR GO; GO:0048260; P:positive regulation of receptor-mediated endocytosis; IEA:Ensembl.
DR GO; GO:0033365; P:protein localization to organelle; IEA:Ensembl.
DR GO; GO:0070507; P:regulation of microtubule cytoskeleton organization; IEA:Ensembl.
DR GO; GO:0016032; P:viral process; IEA:Ensembl.
DR Gene3D; 6.10.250.2470; -; 1.
DR InterPro; IPR018477; BICD.
DR PANTHER; PTHR31233; BICAUDAL D FAMILY MEMBER; 1.
DR PANTHER; PTHR31233:SF3; PROTEIN BICAUDAL D HOMOLOG 1; 1.
DR Pfam; PF09730; BicD; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT REGION 358..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 520..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 775..798
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 812..846
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 84..233
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 294..339
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 395..440
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 642..761
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 360..378
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..587
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 933 AA; 106248 MW; CE0F961C2A357B96 CRC64;
KNTHKKISRA WWWAPVVPQK KTFSQVLKEG YDAFHCALLF FPHTLQAFGQ SFSIHRKVAE
DGETREETLL QESASKEAYY LGKILEMQNE LKQSRAVVTN VQAENERLTA VVQDLKENNE
MVELQRIRMK DEIREYKFRE ARLLQDYTEL EEENITLQKL VSTLKQNQVE YEGLKHEIKR
FEEETVLLNS QLEDAIRLKE IAEHQLEEAL ETLKNEREQK NNLRKELSQY ISLNDNHISI
SVDGLKFAED GSEPNNDDKM NGHIHGPLVK LNGDYRTPTL RKGESLNPVS DLFSELNISE
IQKLRQQLMQ VEREKAILLA NLQESQTQLE HTKGALTEQH ERVHRLTEHV NAMRGLQSSK
ELKAELDGEK GRDSGEEAHD YEVDINGLEI LECKYRVAVT EVIDLKAEIK ALKEKYNKSV
ENYTDEKAKY ESKIQMYDEQ VTGLEKITKE SGEKMAHMEK ELQKMTSIAN ENHYTLNTAQ
DELVTFSEEL AQLYHHVCLC NNETPNRVML DYYRQSRVTR SGSLKGPDDP RGLLSPRLAR
RGVSSPVETR TSSEPVAKES TEASKEPSPT KTPTVSPVIT APPSSPVLDT SDIRKEPMNI
YNLNAIIRDQ IKHLQKAVDR SLQLSRQRAA ARELAPMIDK DKEALMEEIL KLKSLLSTKR
EQIATLRAVL KANKQTAEVA LANLKNKYEN EKAMVTETMT KLRNELKALK EDAATFSSLR
AMFATRCDEY VTQLDEMQRQ LAAAEDEKKT LNTLLRMAIQ QKLALTQRLE DLEFDHEQSR
RSKGKLGKSK IGSPKVSGEA SVTVPTIDTY LLHSQGPQTP NIRVSSGTQR KRQFSPSLCD
QSRPRTSGAS YLQNLLRVPP DPTSTESFLL KGPPSMSELI QGHRLSKEKR LTVAPPGKHF
FLGCIPDTAL PEEQPHSSSQ CAPLHCLSKP PYP
//
