ID M3ZVQ6_XIPMA Unreviewed; 1933 AA.
AC M3ZVQ6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Myosin-7-like {ECO:0000313|Ensembl:ENSXMAP00000006300.2};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000006300.2, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000006300.2}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000006300.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR STRING; 8083.ENSXMAP00000006300; -.
DR Ensembl; ENSXMAT00000006308.2; ENSXMAP00000006300.2; ENSXMAG00000006234.2.
DR eggNOG; KOG0161; Eukaryota.
DR GeneTree; ENSGT00940000154805; -.
DR HOGENOM; CLU_000192_8_1_1; -.
DR InParanoid; M3ZVQ6; -.
DR OMA; MVFRINH; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd01377; MYSc_class_II; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 5.
DR Gene3D; 1.20.5.370; -; 5.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.10.250.2420; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF15; SLOW MYOSIN HEAVY CHAIN 1-RELATED; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000002852}.
FT DOMAIN 32..81
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 85..778
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 655..677
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1584..1607
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 842..1269
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1590..1605
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 178..185
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1933 AA; 222725 MW; 1420ADB865E6DB03 CRC64;
MGDAAMAEFG TAAPFLRKSD RERLEAQTRP FDMKRECFVP DPEVEYVKAT IQSRDGDKVI
ADTELGKTVT VKECDVHPQN PPKFDKIEDM AMFTFLHEPA VLFNLKERYA AWMIYTYSGL
FCVTVNPYKW LPVYNQEVVV AYRGKKRSEA PPHIFSISDN AYQYMLADRE NQSILITGES
GAGKTVNTKR VIQYFASIAA APGVGKKDAA SEKKGTLEDQ IIQANPALEA FGNAKTIRND
NSSRFGKFIR IHFDNRGKLA SADIETYLLE KSRVTYQLRA ERDYHIFYQI LSQVKPELLE
MLLITNNPYD YAFISQGETT VASINDSEEL MATDEAFDVL GFTQEEKNSM YKLTGAIMHH
GNMKFKNKQR EEQAEADGTE DADKAAYLMG LNSADLIKGL CHPRVKVGNE WVTKGQNVAQ
VYYAVGALSK AVYEKMFLWM VVRINQSLDT KQPRQYFIGV LDIAGFEIFD FNTFEQLCIN
FTNEKLQQFF NHHMFVLEQE EYKKEGIEWT FIDFGMDLQA CIDLIEKPMG IMSILEEECM
FPKASDATFK AKLYDNHLGK SNNFQKPRVV KGKPEAHFAL VHYAGTVDYN INNWLVKNKD
PLNETVVGLY QKSTLKLLGI LFANYAGADS GKGKGGTKKK GSSFQTVSAL HRENLNKLMT
NLRSTHPHFV RCIIPNETKT PGAMENPLVM HQLRCNGVLE GIRICRKGFP NRILYGDFKQ
RYRILNPNAI PEGQFIDNKK ASEKLLGSLD IDHNQYKLGH TKVFFKAGLL GLLEEMRDDR
LALIITRIQA RSRGVLARIE FQKIVERRDA LLVIQWNIRA FMGVKNWPWM KLYFKIKPLL
KSAETEKEMA NMKEEFTKLK EAYAKSEARR KELEEKMVSL LQEKNDLQLQ VQTEQDNLSD
AEERCEGLIK SKIQLEAKIK ELTERLEDEE EMNAELTAKK RKLEDECSEL KKDIDDLELT
LAKVEKEKHA TENKVKNLTE EMAALDEIIA KLTKEKKALQ EAHQQTLDDL QSEEDKVNTL
TKAKTKLEQQ VDDLEGSLEQ EKKIRMDLER AKRKLEGDLK LAQESIMDLE NDKQQLEERL
KKKDFEISQL NGKIEDEQAM SAQLQKKLKE LQARIEELEE ELEAERAARA KVEKQRADLA
RELEEISERL EEAGGATAAQ IEMNKKREAE FQKLRRDLEE ATLHHEATTA TLRKKQSDTV
ADLGEQIDNL QRVKQKLEKE KSELRLELDD VVSNMEQIVK AKNNLEKMCR SLEDQLNEYK
TKSEEGQRTI NDFTMQKAKL QTENGELIRM LEEKDSLVSQ LTRGKQSYTQ QIEDLKRQLE
EEIKAKNALA HAVQSARHDC DLLREQYEEE QEAKAELQRS MSKANSEVAQ WRTKYETDAI
QRTEELEEAK KKLAQRLQEA EEAVEAVNAK CSSLEKTKHR LQNEIEDLMV DVERSNAAAA
ALDKKQRNFD KVLSEWKQKY EESQCELESS QKEARSLSTE LFKLKNSYEE SLEHLETMKR
ENKNLQEEIS DLTEQIGVGG KNIHELEKIR KQLEQEKSEI QTALEEAEAS LEHEEGKILR
VQLELNQIKA DFERKLAEKD EEMEQVKRNQ QRMVDTLQSS LESETRSRNE ALRLKKKMEG
DLNEMEIQLS QANRQAAEAQ KQLKSVHAHL KDAQLQLDDA LRGNDDMKEN LAIVERRNNL
LQAELEELRG ALEQTERSRK LAEQELLDVS ERVQLLHSQN TSLINQKKKL EGDIVQLQTE
VEEAVQECRN AEEKAKKAIT DAAMMAEELK KEQDTSAHLE RMKKNMEQTI KDLQHRLDEA
EQIAMKGGKK QVQKLEARVR ELENEVESEQ KKSSDAIKGV RKYERRIKEL TYQTEEDRKN
LARLQDLVDK LQLKVKSYKK SAEVAEEQAN SNLTKFRKIQ HELDEAEERA DIAESQVNKL
RAKSRDAGSK VCM
//
