ID M3ZYM8_XIPMA Unreviewed; 538 AA.
AC M3ZYM8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=E3 ubiquitin-protein ligase NEURL1-like {ECO:0000313|Ensembl:ENSXMAP00000007322.2};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000007322.2, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000007322.2}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000007322.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; M3ZYM8; -.
DR STRING; 8083.ENSXMAP00000007322; -.
DR Ensembl; ENSXMAT00000007330.2; ENSXMAP00000007322.2; ENSXMAG00000007301.2.
DR eggNOG; KOG4172; Eukaryota.
DR eggNOG; KOG4625; Eukaryota.
DR GeneTree; ENSGT00940000156696; -.
DR HOGENOM; CLU_013230_1_0_1; -.
DR InParanoid; M3ZYM8; -.
DR OMA; HRTAIQR; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.920; -; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR037962; Neuralized.
DR InterPro; IPR006573; NHR_dom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12429:SF13; E3 UBIQUITIN-PROTEIN LIGASE NEURL1; 1.
DR PANTHER; PTHR12429; NEURALIZED; 1.
DR Pfam; PF07177; Neuralized; 2.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00588; NEUZ; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51065; NHR; 2.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 33..189
FT /note="NHR"
FT /evidence="ECO:0000259|PROSITE:PS51065"
FT DOMAIN 260..413
FT /note="NHR"
FT /evidence="ECO:0000259|PROSITE:PS51065"
FT DOMAIN 485..525
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 538 AA; 59522 MW; 58B299AB5DC9BC67 CRC64;
AGGQDSRFLQ LLEVFQPKRY PPIQPCGNLS SFPLQFHPST KGSQIIMDLS QRTVKRQASF
CNAITFSNRP IAVYEQVRLK ITKKQCCWSG ALRLGFTSKD PSRINPDSLP KYACPDLVSQ
SGFWAKALPE ELSNEGNVIS FWVDKKGRVF YRINNSNPML FFSGVHVAEP VWALIDVYGL
TRGVQLLDSE MVPLDCLRPR SYAATRRSSA RRNSHDPRLT ISLCDLSLQQ QEMHSNSCHV
PQNSQNSQQC LLLPGHLDTD LQFHTIHGLH VTALDKHTVA RPDHRGDERT LVFTSRPMHC
SEIVFVKVKA GVSRVGSLSY GVTSCDPATL RPSDLPSNPE SLVDRKEFWA VCRVAVQLHS
GDILSFVVNA EGELMMSHNG SSAGMALCVD NSRPLWMFYG LHGSITQLRI LGSSLPLDHQ
GSSVPSSPSC TPNTPTTLCS RNSGSNLNTT LNISLNSNIN PSSPFSSHPQ SPTFPSSSSS
WSDECTICYE NMVDTVLYAC GHMCLCYACG LKLKKMANAC CPICRRTIKD IIKTYRST
//
