ID M4A6J6_XIPMA Unreviewed; 516 AA.
AC M4A6J6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=Coronin {ECO:0000256|RuleBase:RU280818};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000010090.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000010090.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000010090.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat coronin family.
CC {ECO:0000256|RuleBase:RU280818}.
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DR RefSeq; XP_005797653.1; XM_005797596.2.
DR AlphaFoldDB; M4A6J6; -.
DR STRING; 8083.ENSXMAP00000010090; -.
DR Ensembl; ENSXMAT00000010104.2; ENSXMAP00000010090.1; ENSXMAG00000010062.2.
DR GeneID; 102220932; -.
DR KEGG; xma:102220932; -.
DR CTD; 323538; -.
DR eggNOG; KOG0303; Eukaryota.
DR GeneTree; ENSGT00940000155598; -.
DR HOGENOM; CLU_026859_4_0_1; -.
DR InParanoid; M4A6J6; -.
DR OMA; TSCEIFR; -.
DR OrthoDB; 5474889at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR015505; Coronin.
DR InterPro; IPR015048; DUF1899.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR10856; CORONIN; 1.
DR PANTHER; PTHR10856:SF2; CORONIN-2A; 1.
DR Pfam; PF08953; DUF1899; 1.
DR Pfam; PF00400; WD40; 3.
DR Pfam; PF16300; WD40_4; 1.
DR SMART; SM01166; DUF1899; 1.
DR SMART; SM01167; DUF1900; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU280818};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 5..69
FT /note="DUF1899"
FT /evidence="ECO:0000259|SMART:SM01166"
FT REPEAT 78..120
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 128..170
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 176..217
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 435..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 485..512
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 516 AA; 58664 MW; 8FDC3193AAC2DE56 CRC64;
MTWRPQYRSS KFRHVFGKAA TKENCYDGVP ITRSVQDNHF CAVNPRFVAI ITECAGGGAF
LVLSVHHTGK VDPHHPRVSG HRGNVLDIKW NPFNDYCIAS CSEDTTVKVW EIPPHGVLKT
LTVPWKELQG HSRRVGVIEW HPTANNILFS TAYDYQVMIW NLDSPEQVIK NPVRTIKHHT
DVVLSMSFNT DGSLLATTCR DRKIRLMEAR SGNMLQEGSC KTHKASKVLI LGNMKMIFTS
GTSRYNSRQI VLWDQDDLST PLLEENLDGS SGLLFPFYDP DTHMLYLAGK GDGSIRYYEI
SSEKPYIQYL MEYRSHTPQK GMGVMPKRGL DVSSCEVFRF YKVVTVKSLI EPVSMIVPRR
SESYQEDIYP MTASNRPALT ADEWLSGVDK GPILMSLKPG SELMEPPSET KALANSVDAR
RSRSRPGVLQ LSYIQDQQEA KETSDQVEDD RSQTPVINGE DLALCSPPRT ESELRLKFLK
QQEEIRRLRE LLNQREVRVK QLELEIKNIK NSQTQS
//
