ID M4AC96_XIPMA Unreviewed; 569 AA.
AC M4AC96;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Integrin alpha FG-GAP repeat containing 1 {ECO:0000313|Ensembl:ENSXMAP00000012090.2};
GN Name=ITFG1 {ECO:0000313|Ensembl:ENSXMAP00000012090.2};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000012090.2, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000012090.2}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000012090.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TIP family. {ECO:0000256|ARBA:ARBA00006496}.
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DR AlphaFoldDB; M4AC96; -.
DR Ensembl; ENSXMAT00000012106.2; ENSXMAP00000012090.2; ENSXMAG00000012067.2.
DR eggNOG; KOG4550; Eukaryota.
DR GeneTree; ENSGT00390000013367; -.
DR HOGENOM; CLU_020272_2_0_1; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR024881; Tip.
DR PANTHER; PTHR13412:SF0; T-CELL IMMUNOMODULATORY PROTEIN; 1.
DR PANTHER; PTHR13412; T-CELL IMMUNOMODULATORY PROTEIN HOMOLOG; 1.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..569
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017262330"
FT TRANSMEM 524..547
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 569 AA; 64139 MW; F9896DBA2E6F4B23 CRC64;
MLWSCTCSRM RMFTLKTFLI TFLLLLLEQR GIFALQDVTV ELFGTNMYGT VAAFGDFNSD
KQTDIFVIRE LIFLADSKSP YFKPKVNITK DMLDKTITSV VPGDYDGDSQ MDVLLTTQDK
SSETSVFIFW GNNHTLVIPF KNAHFLALSL TATLSFIQNN IESCFPHHFR IQECRNDFNK
SIRMRTPHSN AFIDLDKDFT AGDCGKAKSR VSLQFNPVFL FPDLTLRFIL ADGDGYQDHL
LPACLDEACQ KSVIYIAKRS SEEWVEVLSD FKQRDTVWGF VPGDAIHPLV LHLGDYNLDG
FPDALVILRN TSGSEQRAFL LENAPCNAPN CSSVGRMFRI HWDQTDLGAI QKAVMATFFD
IYEDGILDML ILSEAEGKSD LMIHALKNNF EADAYFVKVM VLSGLCSNAC PDDVKPFGVN
QPGPYVMYTT ADSNGYLKNA SAGQLSQSAH FSLQLPYTVL GLGRSANFLD HLFVGIPRRP
GETETRKHEW TAIIPNSQLI VIPFPHNTPR RWSAKLYLTP SNSVLLTAIA LIGVCVFILV
IIGILHWKEK KADDREKRQE AHRFHFDAM
//
