ID M4AE43_XIPMA Unreviewed; 611 AA.
AC M4AE43;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Phosphoglucomutase 2 {ECO:0000313|Ensembl:ENSXMAP00000012737.2};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000012737.2, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000012737.2}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000012737.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the phosphohexose mutase family.
CC {ECO:0000256|ARBA:ARBA00010231}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_005805087.1; XM_005805030.1.
DR AlphaFoldDB; M4AE43; -.
DR STRING; 8083.ENSXMAP00000012737; -.
DR Ensembl; ENSXMAT00000012753.2; ENSXMAP00000012737.2; ENSXMAG00000012694.2.
DR GeneID; 102218458; -.
DR KEGG; xma:102218458; -.
DR CTD; 55276; -.
DR eggNOG; KOG1220; Eukaryota.
DR GeneTree; ENSGT00940000156247; -.
DR HOGENOM; CLU_016950_0_1_1; -.
DR InParanoid; M4AE43; -.
DR OMA; HVTKASY; -.
DR OrthoDB; 1482at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0016868; F:intramolecular phosphotransferase activity; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd05799; PGM2; 1.
DR Gene3D; 3.40.120.10; Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3; 3.
DR InterPro; IPR005844; A-D-PHexomutase_a/b/a-I.
DR InterPro; IPR016055; A-D-PHexomutase_a/b/a-I/II/III.
DR InterPro; IPR005845; A-D-PHexomutase_a/b/a-II.
DR InterPro; IPR005846; A-D-PHexomutase_a/b/a-III.
DR InterPro; IPR036900; A-D-PHexomutase_C_sf.
DR InterPro; IPR016066; A-D-PHexomutase_CS.
DR InterPro; IPR005841; Alpha-D-phosphohexomutase_SF.
DR PANTHER; PTHR45745; PHOSPHOMANNOMUTASE 45A; 1.
DR PANTHER; PTHR45745:SF3; PHOSPHOPENTOMUTASE; 1.
DR Pfam; PF02878; PGM_PMM_I; 1.
DR Pfam; PF02879; PGM_PMM_II; 1.
DR Pfam; PF02880; PGM_PMM_III; 1.
DR PRINTS; PR00509; PGMPMM.
DR SUPFAM; SSF55957; Phosphoglucomutase, C-terminal domain; 1.
DR SUPFAM; SSF53738; Phosphoglucomutase, first 3 domains; 3.
DR PROSITE; PS00710; PGM_PMM; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002852}.
FT DOMAIN 53..197
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02878"
FT DOMAIN 226..331
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02879"
FT DOMAIN 371..470
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02880"
SQ SEQUENCE 611 AA; 67851 MW; 9C499291C32FF59E CRC64;
MEDGLKPTGD TKLDQAIRQW LRYDRNPKTI SLVQDMVKDG SMEALKKCFS SRMEFGTAGL
RAAMGPGISC MNDLTIIQTT QGFCRYLEQS FGNLKERGVV IGYDARAHPT SGGSSKRFAS
LAAAVFISRG VPVHLFSEIT PTPFVPFTVS HLGLCAGIMV TASHNPKQDN GYKVYWENGA
QIVSPHDSGI SKAIEENLEP WPASWNTEEA LKATLLKDPF QDIKTQYFQA IQKHCHHREI
NKKSEVKIVH TSVHGVGHTF VQSAFKAFDL HPPYPVEEQK DPDPEFPTVK YPNPEEGKGV
LTLSFALAER EGASVVLAND PDADRLAIAE KQESGQWRVF SGNELGTLLG WWMFHCWSEQ
NSDAAAVKNL YMLASTVSSK ILRAIALKEG FHFEETLTGF KWMGNRAKDL LDQGKSVLFA
FEEAIGYMCC NSVLDKDGVS AAAIAGEMIS YLATKSKSLS QQLTTIFEEY GYHISKNSYF
ICHDQEVIRN LFERLRNFGG KKDSYPSECG RFSISAVRDL TTGYDSNQPD KKAILPTSSS
SQMITFTFSN GGVATMRTSG TEPKIKYYTE LCAAPGNSDV THLKKELDDL VDAIVENFFE
PVKNKLQPKP E
//
