ID M4B9V5_HYAAE Unreviewed; 701 AA.
AC M4B9V5;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent)
OS (Peronospora arabidopsidis).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Hyaloperonospora.
OX NCBI_TaxID=559515 {ECO:0000313|EnsemblProtists:HpaP803065, ECO:0000313|Proteomes:UP000011713};
RN [1] {ECO:0000313|Proteomes:UP000011713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Emoy2 {ECO:0000313|Proteomes:UP000011713};
RX PubMed=21148394; DOI=10.1126/science.1195203;
RA Baxter L., Tripathy S., Ishaque N., Boot N., Cabral A., Kemen E.,
RA Thines M., Ah-Fong A., Anderson R., Badejoko W., Bittner-Eddy P.,
RA Boore J.L., Chibucos M.C., Coates M., Dehal P., Delehaunty K., Dong S.,
RA Downton P., Dumas B., Fabro G., Fronick C., Fuerstenberg S.I., Fulton L.,
RA Gaulin E., Govers F., Hughes L., Humphray S., Jiang R.H., Judelson H.,
RA Kamoun S., Kyung K., Meijer H., Minx P., Morris P., Nelson J.,
RA Phuntumart V., Qutob D., Rehmany A., Rougon-Cardoso A., Ryden P.,
RA Torto-Alalibo T., Studholme D., Wang Y., Win J., Wood J., Clifton S.W.,
RA Rogers J., Van den Ackerveken G., Jones J.D., McDowell J.M., Beynon J.,
RA Tyler B.M.;
RT "Signatures of adaptation to obligate biotrophy in the Hyaloperonospora
RT arabidopsidis genome.";
RL Science 330:1549-1551(2010).
RN [2] {ECO:0000313|EnsemblProtists:HpaP803065}
RP IDENTIFICATION.
RC STRAIN=Emoy2 {ECO:0000313|EnsemblProtists:HpaP803065};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
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DR EMBL; JH598048; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M4B9V5; -.
DR STRING; 559515.M4B9V5; -.
DR EnsemblProtists; HpaT803065; HpaP803065; HpaG803065.
DR VEuPathDB; FungiDB:HpaG803065; -.
DR eggNOG; KOG0134; Eukaryota.
DR eggNOG; KOG1800; Eukaryota.
DR HOGENOM; CLU_012153_1_1_1; -.
DR InParanoid; M4B9V5; -.
DR OMA; WGGDYAR; -.
DR Proteomes; UP000011713; Unassembled WGS sequence.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd02930; DCR_FMN; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR001155; OxRdtase_FMN_N.
DR PANTHER; PTHR42917; 2,4-DIENOYL-COA REDUCTASE; 1.
DR PANTHER; PTHR42917:SF2; 2,4-DIENOYL-COA REDUCTASE [(2E)-ENOYL-COA-PRODUCING]; 1.
DR Pfam; PF00724; Oxidored_FMN; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF51395; FMN-linked oxidoreductases; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011713}.
FT DOMAIN 7..328
FT /note="NADH:flavin oxidoreductase/NADH oxidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00724"
FT DOMAIN 374..639
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 701 AA; 76134 MW; 097A4602950D324E CRC64;
MSKYPHLLQP LDLGFTQLKN RILMGSMHTG LEEGKSLTRL AAFFAERARG NVGLIVTGGI
APNRAGRVSP LAAKLTTQGE VTAHREVTKA VHDHDGKIAM QILHSGRYGY HPFTVAPSAI
KAPIGWFTPK ALSSAAVRST IRDYANCAAR AREAGYDGVE IMGSEGYLIN QFIVEHTNTR
KDEWGGSYEH RIRFPIEIVK AVRAAVGNDF ILIFRLSMLD LVERGSTWDE IVMLAKQIEA
AGATIINTGI GWHEARIPTI ATSVPRGGFS WVTQKMKGEV SIPLITTNRI NMPDVAEQII
AEGRAVSMAR PFLADPEFAR KTEEDRVDEI NTCIGCNQAC LDHTFKGITA SCLVNPRSGY
ETLLNYTPTN NVQRVAVVGS GPAGLSFSTT AALRGHEVTL FDQADAIGGQ FNMAKIVPGK
EEFYETLRYF EKQLKLRGVN VKLGHRVEAA ELMSGAFDKV VIATGVVPRS LTIPGADHPK
VLSYIDVLKN EAPVGQKVAI IGAGGIGFDV AEFLTHEGES SSSSIDAFAR EWGIDTSNTV
RGGVAGIQPS ILPPSREVYL IQRKSTKHGK DLGKTTGWIH RLSLKHRNVK MIGGVSYDKV
DDAGLHYTDK NGKKKVLDVD NVVVCVGQVP LRELEKPLQE KGIIVFRIGG ADEAGELDAK
RAIDQGARLA ATIETAKPGD PLEATPPLSA KVFEFLSKFQ Q
//
