ID M4BD16_HYAAE Unreviewed; 927 AA.
AC M4BD16;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein {ECO:0000259|Pfam:PF02096};
OS Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent)
OS (Peronospora arabidopsidis).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Hyaloperonospora.
OX NCBI_TaxID=559515 {ECO:0000313|EnsemblProtists:HpaP804183, ECO:0000313|Proteomes:UP000011713};
RN [1] {ECO:0000313|Proteomes:UP000011713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Emoy2 {ECO:0000313|Proteomes:UP000011713};
RX PubMed=21148394; DOI=10.1126/science.1195203;
RA Baxter L., Tripathy S., Ishaque N., Boot N., Cabral A., Kemen E.,
RA Thines M., Ah-Fong A., Anderson R., Badejoko W., Bittner-Eddy P.,
RA Boore J.L., Chibucos M.C., Coates M., Dehal P., Delehaunty K., Dong S.,
RA Downton P., Dumas B., Fabro G., Fronick C., Fuerstenberg S.I., Fulton L.,
RA Gaulin E., Govers F., Hughes L., Humphray S., Jiang R.H., Judelson H.,
RA Kamoun S., Kyung K., Meijer H., Minx P., Morris P., Nelson J.,
RA Phuntumart V., Qutob D., Rehmany A., Rougon-Cardoso A., Ryden P.,
RA Torto-Alalibo T., Studholme D., Wang Y., Win J., Wood J., Clifton S.W.,
RA Rogers J., Van den Ackerveken G., Jones J.D., McDowell J.M., Beynon J.,
RA Tyler B.M.;
RT "Signatures of adaptation to obligate biotrophy in the Hyaloperonospora
RT arabidopsidis genome.";
RL Science 330:1549-1551(2010).
RN [2] {ECO:0000313|EnsemblProtists:HpaP804183}
RP IDENTIFICATION.
RC STRAIN=Emoy2 {ECO:0000313|EnsemblProtists:HpaP804183};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU003945}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003945}.
CC Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family.
CC {ECO:0000256|RuleBase:RU003945}.
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DR EMBL; JH598146; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M4BD16; -.
DR STRING; 559515.M4BD16; -.
DR EnsemblProtists; HpaT804183; HpaP804183; HpaG804183.
DR VEuPathDB; FungiDB:HpaG804183; -.
DR eggNOG; KOG1239; Eukaryota.
DR eggNOG; KOG4379; Eukaryota.
DR HOGENOM; CLU_014227_0_0_1; -.
DR InParanoid; M4BD16; -.
DR OMA; ESAMITT; -.
DR Proteomes; UP000011713; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR GO; GO:0051205; P:protein insertion into membrane; IEA:UniProt.
DR CDD; cd20069; 5TM_Oxa1-like; 1.
DR InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR InterPro; IPR028055; YidC/Oxa/ALB_C.
DR NCBIfam; TIGR03592; yidC_oxa1_cterm; 1.
DR PANTHER; PTHR12428:SF34; CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12428; OXA1; 1.
DR Pfam; PF02096; 60KD_IMP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Reference proteome {ECO:0000313|Proteomes:UP000011713};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003945};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 677..700
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 835..856
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 679..869
FT /note="Membrane insertase YidC/Oxa/ALB C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02096"
FT REGION 343..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..366
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 927 AA; 101802 MW; 208FC6052F2AC5BF CRC64;
MASGHMEVHR AFIDNAFDRY VLATGDELTK RATALSAPAL APLLADPGMR KKAHWEARVH
HNALTLDPFL SQSYGATVAY FVNASYQLVQ VLEHKTRGVK FKGVYDLPQL AARQENVSVQ
VAGKGSVVYC DGHGTLHCLT AETDQEGSKW SQVYECAPWG VVPLLLVGAF YDAQHHHLRA
VVAEPLFGNG EDRAFRLSVV RILLPTASTT QSGMEVVPTE LELNHVTSTI AVVSKLPTLV
SFSGPDVVLL VEGTYELLMK LVADKSKRTV VNVVPVATGV SVGHVRRHDE DNLTDDGMTD
LLSAFPRAGI GFHGDITKPK DPSELALVDF KTSLTDRFHK SSTPFSSVAT PLNEAPPAST
HQNKEGASRT LGHRCEVPTA ESLLSGFEEC DSGDPNARAS LLLVNYEQQV VQHQLGIDCM
QFQFLCPSAR VQDSSDYKSA LLFRNDVHGL IFELNVTGDP LTLLHTATLP AFGFVQASKQ
EKKFMSCHAS GSLACIGEFQ RRVFMYQGKS SETDRESHTR KQHVVEFGDQ EILGMQIADE
NTVLLLQPYK KATFSTQSAA MLLSMRQMRP AVTSMARSVA RSGPRIAQTD CSLRFEHAVA
GRLIPTHFCN GRSFSSSPVV GLATDDRVVE GSHVEGAEQA LDAAASAVDY ASVSDLGYGL
SDIAIRSLDL IHSTTGLPWW ATIIATTVAV RTVFFPITVV SMRNAAKMKL FQPDMEKLRN
EMDANPTRDP ESVKEFQKKY KTLMKKHDVN PLKSMLTPLA QIPVFIGFFW GLQDISKYFP
EYAHEGIGWV KDLSVADPTT ALPVISSALL VASVELGGDA MTGEMKDKMK FGMRCFAVLM
VPLTMNFQSG IFVYWVTSNM YTLTQTALLR LNFVKRAFNI PVTEVQRLET SSVTMTSPFE
AAVARAKEGT IVKTHMYKPT KPSKKKQ
//
