ID M4BST4_HYAAE Unreviewed; 383 AA.
AC M4BST4;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=tetraacyldisaccharide 4'-kinase {ECO:0000256|ARBA:ARBA00012071};
DE EC=2.7.1.130 {ECO:0000256|ARBA:ARBA00012071};
OS Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent)
OS (Peronospora arabidopsidis).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Hyaloperonospora.
OX NCBI_TaxID=559515 {ECO:0000313|EnsemblProtists:HpaP809519, ECO:0000313|Proteomes:UP000011713};
RN [1] {ECO:0000313|Proteomes:UP000011713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Emoy2 {ECO:0000313|Proteomes:UP000011713};
RX PubMed=21148394; DOI=10.1126/science.1195203;
RA Baxter L., Tripathy S., Ishaque N., Boot N., Cabral A., Kemen E.,
RA Thines M., Ah-Fong A., Anderson R., Badejoko W., Bittner-Eddy P.,
RA Boore J.L., Chibucos M.C., Coates M., Dehal P., Delehaunty K., Dong S.,
RA Downton P., Dumas B., Fabro G., Fronick C., Fuerstenberg S.I., Fulton L.,
RA Gaulin E., Govers F., Hughes L., Humphray S., Jiang R.H., Judelson H.,
RA Kamoun S., Kyung K., Meijer H., Minx P., Morris P., Nelson J.,
RA Phuntumart V., Qutob D., Rehmany A., Rougon-Cardoso A., Ryden P.,
RA Torto-Alalibo T., Studholme D., Wang Y., Win J., Wood J., Clifton S.W.,
RA Rogers J., Van den Ackerveken G., Jones J.D., McDowell J.M., Beynon J.,
RA Tyler B.M.;
RT "Signatures of adaptation to obligate biotrophy in the Hyaloperonospora
RT arabidopsidis genome.";
RL Science 330:1549-1551(2010).
RN [2] {ECO:0000313|EnsemblProtists:HpaP809519}
RP IDENTIFICATION.
RC STRAIN=Emoy2 {ECO:0000313|EnsemblProtists:HpaP809519};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- PATHWAY: Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A)
CC from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-
CC acetyl-alpha-D-glucosamine: step 6/6. {ECO:0000256|ARBA:ARBA00004870}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH597790; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M4BST4; -.
DR STRING; 559515.M4BST4; -.
DR EnsemblProtists; HpaT809519; HpaP809519; HpaG809519.
DR VEuPathDB; FungiDB:HpaG809519; -.
DR eggNOG; ENOG502QRUA; Eukaryota.
DR HOGENOM; CLU_038816_6_2_1; -.
DR InParanoid; M4BST4; -.
DR OMA; IVIVTKC; -.
DR UniPathway; UPA00359; UER00482.
DR Proteomes; UP000011713; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0009029; F:tetraacyldisaccharide 4'-kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR HAMAP; MF_00409; LpxK; 1.
DR InterPro; IPR003758; LpxK.
DR PANTHER; PTHR42724; TETRAACYLDISACCHARIDE 4'-KINASE; 1.
DR PANTHER; PTHR42724:SF1; TETRAACYLDISACCHARIDE 4'-KINASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF02606; LpxK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Lipid A biosynthesis {ECO:0000256|ARBA:ARBA00022556};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000011713};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 383 AA; 43239 MW; 7BB47EEF9D649B95 CRC64;
MAQVWRRWHR KWHGTILAAL RSNHWPIDVL IDRKQPIPSR IYSWIITCTR QRDSSCKERM
APSYVPVLSV GNVTFGGTGK TPFVQFLLDY ISKRGDKGHV PLVLSRGYGD DEWRMLIKRF
PACEVALGRD RVAAGDAKVK ELGADTAPLS CVVLDDGLQQ WRVAKDLEIV MVDALHPLGN
GLLLPCGSLR ELPRDAFARA DVVVIHHANL VESERVHELM GSLRGLMDPR RRPIVAMSRM
KITKLVSVDK VLPSAMSDST INLERDDSCL DGLFVLIVCG VGNPESVKKV VANWACWAHM
EVQAFPDHHP FTQGDMHDIL ERAREIQRSE SLVVVTTEKD FARSPVAMQL LAEKVDLRVL
HCELELLYNC QQVKKRIDSC FNK
//
