ID M4C333_HYAAE Unreviewed; 573 AA.
AC M4C333;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=phospholipase D {ECO:0000256|ARBA:ARBA00012027};
DE EC=3.1.4.4 {ECO:0000256|ARBA:ARBA00012027};
OS Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent)
OS (Peronospora arabidopsidis).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Hyaloperonospora.
OX NCBI_TaxID=559515 {ECO:0000313|EnsemblProtists:HpaP813500, ECO:0000313|Proteomes:UP000011713};
RN [1] {ECO:0000313|Proteomes:UP000011713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Emoy2 {ECO:0000313|Proteomes:UP000011713};
RX PubMed=21148394; DOI=10.1126/science.1195203;
RA Baxter L., Tripathy S., Ishaque N., Boot N., Cabral A., Kemen E.,
RA Thines M., Ah-Fong A., Anderson R., Badejoko W., Bittner-Eddy P.,
RA Boore J.L., Chibucos M.C., Coates M., Dehal P., Delehaunty K., Dong S.,
RA Downton P., Dumas B., Fabro G., Fronick C., Fuerstenberg S.I., Fulton L.,
RA Gaulin E., Govers F., Hughes L., Humphray S., Jiang R.H., Judelson H.,
RA Kamoun S., Kyung K., Meijer H., Minx P., Morris P., Nelson J.,
RA Phuntumart V., Qutob D., Rehmany A., Rougon-Cardoso A., Ryden P.,
RA Torto-Alalibo T., Studholme D., Wang Y., Win J., Wood J., Clifton S.W.,
RA Rogers J., Van den Ackerveken G., Jones J.D., McDowell J.M., Beynon J.,
RA Tyler B.M.;
RT "Signatures of adaptation to obligate biotrophy in the Hyaloperonospora
RT arabidopsidis genome.";
RL Science 330:1549-1551(2010).
RN [2] {ECO:0000313|EnsemblProtists:HpaP813500}
RP IDENTIFICATION.
RC STRAIN=Emoy2 {ECO:0000313|EnsemblProtists:HpaP813500};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; ABWE02002581; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M4C333; -.
DR STRING; 559515.M4C333; -.
DR EnsemblProtists; HpaT813500; HpaP813500; HpaG813500.
DR VEuPathDB; FungiDB:HpaG813500; -.
DR eggNOG; KOG1329; Eukaryota.
DR HOGENOM; CLU_023720_1_0_1; -.
DR InParanoid; M4C333; -.
DR OMA; DFENPQY; -.
DR Proteomes; UP000011713; Unassembled WGS sequence.
DR GO; GO:0070290; F:N-acylphosphatidylethanolamine-specific phospholipase D activity; IEA:UniProtKB-EC.
DR GO; GO:0004630; F:phospholipase D activity; IEA:UniProtKB-EC.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd09105; PLDc_vPLD1_2_like_2; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR InterPro; IPR015679; PLipase_D_fam.
DR PANTHER; PTHR18896; PHOSPHOLIPASE D; 1.
DR PANTHER; PTHR18896:SF60; PHOSPHOLIPASE D; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022963};
KW Reference proteome {ECO:0000313|Proteomes:UP000011713};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..573
FT /note="phospholipase D"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004049179"
FT DOMAIN 446..473
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 573 AA; 64347 MW; 1455D7B4C18071E7 CRC64;
MRPRATSILI VGCVQLVLAS SASASWSFLN FFGDKKNDDR SGGNGSSPTD LVTNVLQDEV
EFEQPLLVAA DWFLTEEEIT ASRGGVPRLN MVTYSTGNNV KTFTVTKEFF DSLYNDLSST
KANDRVMVTS YNTALIPFKP ETDPEGITSR FDAVFGGVVK RGGDVKIICW ATKFPSKQDI
NVRDKINELP TSGINNGSAQ FIFDDRLPYS LSSHHQKTVI IAASAPSGAD KYPVAYVGGI
DITNDRWDTI YHNESALREK AGINLDYKGW VDSSLRIHGP AAKDVAANFL DRWNSPYLPT
QDLVDNLESF QNPQYSFQPA LNYSSSNTTS TLGHQSVQIV RTFSCKYKHY EFAPFGEKSL
LYARIKAIKN AKNFIYVEDQ YFIHVPELLD ALMVVLPIIQ RLVVVIQPPE LMTKSGGYEK
YMYKLVQPIK DKFPDKIRMY SMKPELNVYV HSKIVIIDDV YLSDGSANWN RRSMTSDVEL
NANIVDLKTV DSPDGVTVGK LVRDFRVRKF HEMTGRSYKE INKMKFLDSA DLFDAAAAEK
GSLIKKFDIG KKLYYNVIGK GLHQGIDPYD HCN
//
