ID M4RXD5_9SPHN Unreviewed; 471 AA.
AC M4RXD5;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE RecName: Full=Phospholipase D {ECO:0000256|ARBA:ARBA00018392};
DE AltName: Full=Choline phosphatase {ECO:0000256|ARBA:ARBA00029594};
GN ORFNames=G432_02415 {ECO:0000313|EMBL:AGH48211.1};
OS Sphingomonas sp. MM-1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=745310 {ECO:0000313|EMBL:AGH48211.1, ECO:0000313|Proteomes:UP000011816};
RN [1] {ECO:0000313|EMBL:AGH48211.1, ECO:0000313|Proteomes:UP000011816}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MM-1 {ECO:0000313|EMBL:AGH48211.1};
RX PubMed=23682148;
RA Tabata M., Ohtsubo Y., Ohhata S., Tsuda M., Nagata Y.;
RT "Complete Genome Sequence of the gamma-Hexachlorocyclohexane-Degrading
RT Bacterium Sphingomonas sp. Strain MM-1.";
RL Genome Announc. 1:E00247-13(2013).
CC -!- FUNCTION: Could be a virulence factor. {ECO:0000256|ARBA:ARBA00003145}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; CP004036; AGH48211.1; -; Genomic_DNA.
DR RefSeq; WP_015457227.1; NC_020561.1.
DR AlphaFoldDB; M4RXD5; -.
DR STRING; 745310.G432_02415; -.
DR KEGG; sphm:G432_02415; -.
DR PATRIC; fig|745310.14.peg.495; -.
DR eggNOG; COG1502; Bacteria.
DR HOGENOM; CLU_038053_1_0_5; -.
DR Proteomes; UP000011816; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008808; F:cardiolipin synthase activity; IEA:InterPro.
DR GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:InterPro.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR022924; Cardiolipin_synthase.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR NCBIfam; TIGR04265; bac_cardiolipin; 1.
DR PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR PANTHER; PTHR21248:SF22; PHOSPHOLIPASE D; 1.
DR Pfam; PF13091; PLDc_2; 2.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011816};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 213..240
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 384..411
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 471 AA; 52731 MW; 71CEFE4596A552FC CRC64;
MAIHDIPSLG ESYYLVEWAI RLVMLVVVPF RRSPAATRSW LLLIFVLPLP GLLLFLAIGS
PRFPRWRRER FHALDPFVAG LAARLDAEAP PGAMNEPEAA TLARTLGHLP AVGGNAVEFI
DDYDAVIDRL VEDIDAAKRH VRLLVYIFAD DAVGQRVMAA LARAVARGVA CHVLFDPVGS
HRWRRGTVAG LRAAGVEVRA ALPFRLLRDR TRRDMRNHRK LFLIDGQVGF TGSQNIVAQD
FRPGVTNREL VVRVTGPVVA EMTAVFLADW YLETERLLED APEISPAAGT ATAQVLPSGA
DYRSQGFHTM LIWQIHRARH RVVLVTPYLI PDEDLLSALR TAVLRGVTVD LVVSAIVDQR
LVHFAQSSYY DELLRSGVRI RRYRRRLLHA KNVAFDDRLA ILGSSNIDIR SFELNEEVSL
LLFDAADIAR LTAIQQGYLA ESDEVTLDQW RRRSGLRKFA ENVARLVSPL L
//
