ID M4ZQM4_STRCA Unreviewed; 418 AA.
AC M4ZQM4;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Lamin B1 {ECO:0000313|EMBL:BAM99022.1};
DE Flags: Fragment;
GN Name=LMNB1 {ECO:0000313|EMBL:BAM99022.1};
OS Struthio camelus (Common ostrich).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC Struthio.
OX NCBI_TaxID=8801 {ECO:0000313|EMBL:BAM99022.1};
RN [1] {ECO:0000313|EMBL:BAM99022.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Testes {ECO:0000313|EMBL:BAM99022.1};
RA Kawagoshi T., Nishida C., Matsuda Y.;
RT "The same origin but independent evolution of Staurotypus turtles XY.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Lamins are components of the nuclear lamina, a fibrous layer
CC on the nucleoplasmic side of the inner nuclear membrane, which is
CC thought to provide a framework for the nuclear envelope and may also
CC interact with chromatin. {ECO:0000256|ARBA:ARBA00037635}.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; AB747282; BAM99022.1; -; mRNA.
DR AlphaFoldDB; M4ZQM4; -.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005635; C:nuclear envelope; IEA:UniProt.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.60.40.1260; Lamin Tail domain; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR001322; Lamin_tail_dom.
DR InterPro; IPR036415; Lamin_tail_dom_sf.
DR PANTHER; PTHR45721; LAMIN DM0-RELATED; 1.
DR PANTHER; PTHR45721:SF3; LAMIN-B1; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF00932; LTD; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 1.
DR SUPFAM; SSF74853; Lamin A/C globular tail domain; 1.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
DR PROSITE; PS51841; LTD; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023289};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Prenylation {ECO:0000256|ARBA:ARBA00023289}.
FT DOMAIN 1..286
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT DOMAIN 328..418
FT /note="LTD"
FT /evidence="ECO:0000259|PROSITE:PS51841"
FT REGION 285..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 19..120
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 184..264
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 290..306
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:BAM99022.1"
FT NON_TER 418
FT /evidence="ECO:0000313|EMBL:BAM99022.1"
SQ SEQUENCE 418 AA; 47672 MW; 6C5DDA4F0DC9D84A CRC64;
LQIELGKIRA EHEQLLGSYA KKESDLNGAQ VKLREFEAAL NSKEAALATA LGDKKSLEGE
LEDLRDQIAQ LEVSLAAAKK QLADETLMKV DLENRCQSLI EDLEFRKNMY EEEINETRRK
HETRLVEVDS GRQIEYEHKL AQALHEIREQ HDAQVKLYKE ELEQTYHAKL ENARLSSEMS
TSTANSVREE LTESRMRIEN LSSQLASLQK ESRAWQDRMQ ELEDTLAKER ENCRKMLSDK
EREMAEIRDQ MQQQLSDYEQ LLDVKLALDM EINAYRKLLE GEEERLKLSP SPSSRVTVSR
ASSSRSVRTT RGKRKRIDVE ESEASSSVSI SHSASATGNV SIEEIDVDGK FIRLKNTSEQ
DQPMGGWEMI RKIGDTSATY KYTSRYVLKA GQTVTIWAAN AGVTASPPTD LIWKNQNS
//
