ID M5B9K8_9MICO Unreviewed; 561 AA.
AC M5B9K8;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=dctS {ECO:0000313|EMBL:CCE75809.1};
GN ORFNames=CMN_01864 {ECO:0000313|EMBL:CCE75809.1};
OS Clavibacter nebraskensis NCPPB 2581.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Clavibacter.
OX NCBI_TaxID=1097677 {ECO:0000313|EMBL:CCE75809.1, ECO:0000313|Proteomes:UP000012170};
RN [1] {ECO:0000313|EMBL:CCE75809.1, ECO:0000313|Proteomes:UP000012170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCPPB 2581 {ECO:0000313|Proteomes:UP000012170};
RA Gartemann K.;
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CCE75809.1, ECO:0000313|Proteomes:UP000012170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCPPB 2581 {ECO:0000313|Proteomes:UP000012170};
RA Gartemann K.H., Blom J., Dreiseikelmann B., Fluegel M., Jaenicke S.,
RA Linke B., Sczcepanowski R., Wittmann J., Goesmann A., Puehler A.,
RA Eichenlaub R., Rueckert C.;
RT "The genome sequence of the maize-pathogen Clavibacter michiganensis subsp.
RT nebraskensis.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; HE614873; CCE75809.1; -; Genomic_DNA.
DR AlphaFoldDB; M5B9K8; -.
DR KEGG; cmc:CMN_01864; -.
DR HOGENOM; CLU_020211_11_1_11; -.
DR Proteomes; UP000012170; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR033463; sCache_3.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR016120; Sig_transdc_His_kin_SpoOB.
DR PANTHER; PTHR45436:SF5; SENSOR HISTIDINE KINASE TRCS; 1.
DR PANTHER; PTHR45436; SENSOR HISTIDINE KINASE YKOH; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF17203; sCache_3_2; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR SUPFAM; SSF55890; Sporulation response regulatory protein Spo0B; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:CCE75809.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 169..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 338..542
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 540..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..561
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 561 AA; 57989 MW; 14188445ED6F91E2 CRC64;
MGLPRGIAAR LLVVQLAVLL LVAVVATAAL WADSRQRAEQ AAADRSLAVA TTVADSPRVA
EGLASADPTA ALLDYSLDVT RDTGVDFVTI MDRDTVRVTH PDPDEIGRRY LGTTGPALAG
RSMTETFTGT LGPSVRAVVP VRDADGGIVG LVAAGVTVDR VTEVLGARLP GLVGTVGALA
LLVAAGAVLL SRSLERTTWG LGPEEMARML AYYESVLHSV GEGIVLVDRD RRLVLHNDQA
AELLELELDP ATGPVEVSAL GLPPAIERLL VEGTTADEVV HLPSGRVLVV TQRPALPTGR
TGSAARLGTV TTLRDRTEIL RLSGELATLR TLSDAMRAQT HEFANRLHTI VSLIELERPR
EALALAASEL ETDRRASEGG LAADADPVVR ALVCGKTAQA AERGVRLSVR VADGTGDPGV
PATELVTIVG NLVDNAIDAA ADPSVATARG DDRGRVELSL SRTDAGGLVV EVADDGPGVD
PAVRPRVLEF GVTTKAGDAG PRGVGLALVA RSAARLGGRV EVGDADAPLG GARVRVVLPA
EPRTAAADPD RADARDGGVR A
//
