ID   M5DRI4_9GAMM            Unreviewed;       788 AA.
AC   M5DRI4;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=Integral membrane protein {ECO:0000313|EMBL:CCU71777.1};
GN   ORFNames=TOL_1352 {ECO:0000313|EMBL:CCU71777.1};
OS   Thalassolituus oleivorans MIL-1.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Oceanospirillaceae; Thalassolituus.
OX   NCBI_TaxID=1298593 {ECO:0000313|EMBL:CCU71777.1, ECO:0000313|Proteomes:UP000011866};
RN   [1] {ECO:0000313|EMBL:CCU71777.1, ECO:0000313|Proteomes:UP000011866}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MIL-1 {ECO:0000313|EMBL:CCU71777.1,
RC   ECO:0000313|Proteomes:UP000011866};
RX   PubMed=23599290; DOI=10.1128/genomeA.00141-13;
RA   Golyshin P.N., Werner J., Chernikova T.N., Tran H., Ferrer M.,
RA   Yakimov M.M., Teeling H., Golyshina O.V.;
RT   "Genome Sequence of Thalassolituus oleivorans MIL-1 (DSM 14913T).";
RL   Genome Announc. 1:1-3(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; HF680312; CCU71777.1; -; Genomic_DNA.
DR   RefSeq; WP_015486510.1; NC_020888.1.
DR   AlphaFoldDB; M5DRI4; -.
DR   STRING; 187493.CN03_11475; -.
DR   KEGG; tol:TOL_1352; -.
DR   PATRIC; fig|1298593.3.peg.1290; -.
DR   eggNOG; COG1033; Bacteria.
DR   HOGENOM; CLU_008861_1_0_6; -.
DR   Proteomes; UP000011866; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011866};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        222..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        248..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        277..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        318..339
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        359..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        400..417
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        600..622
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        629..649
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        655..676
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        696..718
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        730..755
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          248..373
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
FT   DOMAIN          627..754
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   788 AA;  86181 MW;  D841D7F40A3F3498 CRC64;
     MKAIMQRWIV DHPVILLVLF LVLSVLAAAG GKNLTFRGDY KIYFEEGYAP LNDFEEMQGI
     FNKNDNIAVL MVPKDGEVFT PEFLTLVKDY TEAAWQTPYS SRVDSLTNFQ HTWSEEDDMI
     VEDLVLDPES LTADDLTRIR SIALAEPALK GRMVSASGEV ALVNVTLQLP SATDNTAYVA
     EVMASVKALS KTFAEQYPSV EFFHTGVLPM NSSFATEGQK DMSTLIPAML LLIIVLLAVL
     LRSILAMLAT IIVLVLSVAA TMGLGGWTGF FLSTGTINVP IVVLTIAVAD CVHMIATMQF
     AMRQGKTRAQ AVQYSVDLNW MPVFITSATT AIGFMTLAFS ESPVFADFGI LSAMGVMTAY
     LLSVTLFPAI LMLLPIKVGK ATNDSKGMAR LADFIVARQR ALLVGGAILI VAVGSLITKN
     QINDVATAYF SDATEFRQSV NKQEDTLSGS QSIDWALYSG IEGGVSEPEF IETVRGFSEW
     LRAQPEVDHV STISDTFKRL NLNMHGDDSE WYRIPEEREL AAQYLLLYEM SLPYGLDLNN
     QINIDKSSTR VTSTLKNLGS REIVDLEQRA QAWIAEHAPN VRMAGASPGL MFAHIGEANM
     HSMIISMAVA MVLISAILVF ALRSVRLGAI SLIPNLAPAV VGFGVWGVMS GEINLGLSIV
     TSMTLGIIVD DTVHFLSKYQ RARKDGLDTE AAIRYAFISV GRALIITTVV LVMGFYILSF
     SSFRLNSDMG MATSMIIAIA LVIDFFFLPP LLLWLDRDET DKSTIKNQSK GAEKLLEADI
     AETKGEIA
//