ID M5E7S0_MALS4 Unreviewed; 643 AA.
AC M5E7S0;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Heat shock protein that is highly induced upon stress {ECO:0000313|EMBL:SHO79397.1};
GN Name=SSA4 {ECO:0000313|EMBL:SHO79397.1};
GN ORFNames=MSYG_3746 {ECO:0000313|EMBL:SHO79397.1};
OS Malassezia sympodialis (strain ATCC 42132) (Atopic eczema-associated
OS yeast).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX NCBI_TaxID=1230383 {ECO:0000313|EMBL:SHO79397.1, ECO:0000313|Proteomes:UP000186303};
RN [1] {ECO:0000313|Proteomes:UP000186303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42132 {ECO:0000313|Proteomes:UP000186303};
RX PubMed=28100699; DOI=10.1093/nar/gkx006;
RA Zhu Y., Engstroem P.G., Tellgren-Roth C., Baudo C.D., Kennell J.C., Sun S.,
RA Billmyre R.B., Schroeder M.S., Andersson A., Holm T., Sigurgeirsson B.,
RA Wu G., Sankaranarayanan S.R., Siddharthan R., Sanyal K., Lundeberg J.,
RA Nystedt B., Boekhout T., Dawson T.L. Jr., Heitman J., Scheynius A.,
RA Lehtioe J.;
RT "Proteogenomics produces comprehensive and highly accurate protein-coding
RT gene annotation in a complete genome assembly of Malassezia sympodialis.";
RL Nucleic Acids Res. 45:2629-2643(2017).
CC -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|RuleBase:RU003322}.
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DR EMBL; LT671826; SHO79397.1; -; Genomic_DNA.
DR RefSeq; XP_018739877.1; XM_018886399.1.
DR STRING; 1230383.M5E7S0; -.
DR GeneID; 30056170; -.
DR KEGG; msym:MSY001_1285; -.
DR VEuPathDB; FungiDB:MSYG_3746; -.
DR HOGENOM; CLU_005965_7_0_1; -.
DR OMA; KANPIMM; -.
DR OrthoDB; 143at2759; -.
DR Proteomes; UP000186303; Chromosome 6.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR CDD; cd10233; HSPA1-2_6-8-like_NBD; 1.
DR Gene3D; 1.20.1270.10; -; 1.
DR Gene3D; 3.30.30.30; -; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018181; Heat_shock_70_CS.
DR InterPro; IPR029048; HSP70_C_sf.
DR InterPro; IPR029047; HSP70_peptide-bd_sf.
DR InterPro; IPR013126; Hsp_70_fam.
DR PANTHER; PTHR19375:SF395; HEAT SHOCK 70 KDA PROTEIN COGNATE 1-RELATED; 1.
DR PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR Pfam; PF00012; HSP70; 1.
DR PRINTS; PR00301; HEATSHOCK70.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF100934; Heat shock protein 70kD (HSP70), C-terminal subdomain; 1.
DR SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR PROSITE; PS00297; HSP70_1; 1.
DR PROSITE; PS00329; HSP70_2; 1.
DR PROSITE; PS01036; HSP70_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003322};
KW Reference proteome {ECO:0000313|Proteomes:UP000186303};
KW Stress response {ECO:0000313|EMBL:SHO79397.1}.
SQ SEQUENCE 643 AA; 70172 MW; E991F4F4389BABCA CRC64;
MGKAVGIDLG TTYSCVAVWQ NDRVEVIAND QGNRTTPSYV AFTDTERLIG DAAKNQVAMN
PHNTVFDAKR LIGRKFNDTE VQSDMKHWPF SVIDRSGKPV IRVEYKGEEK IFTPEEISSM
VLLKMRETAE AYLGSDVKDA VVTVPAYFND SQRQATKDAG VIAGLNVMRI INEPTAAAIA
YGLDKKDESE KNVLIFDLGG GTFDVSLLTI EEGIFEVKAT AGDTHLGGED FDNRLVNHFV
QEFKRKNKKD LTTNARALRR LRTASERAKR TLSSAAQTTI EIDSLFEGID FYTSITRARF
EELCGDLFSH TIDPVEKVLR DAKIDKGSVN EIVLVGGSTR IPRVQKLLRD FFNGREPNKS
INPDEAVAYG AAVQAAILSG DTSEKTQDLL LLDVAPLSMG IETAGGVFTP LIKRNTTVPT
KKSEVFSTYA DNQPGVLIQV FEGERARTKD NNLLGKFELS GIPPAPRGVP QIEVTFDVDA
NAILNVSAAD KTTGRSEKIT ITNDKGRLSK EDIERMVADA EKYKAEDEAA AERIKSKNGL
ESYTYNLRNS LNEEAFASKL DASDKETLKK AIDETIEWLD NTQEGSIDEY NDKQKELEGI
ANPIMQKAYS AAGGAPGGGF PGADAGAAPG AGGDDGPQVE EID
//
