ID M5PTY0_DESAF Unreviewed; 275 AA.
AC M5PTY0;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase {ECO:0000313|EMBL:EMG37807.1};
GN ORFNames=PCS_01457 {ECO:0000313|EMBL:EMG37807.1};
OS Desulfocurvibacter africanus PCS.
OC Bacteria; Thermodesulfobacteriota; Desulfovibrionia; Desulfovibrionales;
OC Desulfovibrionaceae; Desulfocurvibacter.
OX NCBI_TaxID=1262666 {ECO:0000313|EMBL:EMG37807.1, ECO:0000313|Proteomes:UP000011922};
RN [1] {ECO:0000313|EMBL:EMG37807.1, ECO:0000313|Proteomes:UP000011922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCS {ECO:0000313|EMBL:EMG37807.1,
RC ECO:0000313|Proteomes:UP000011922};
RX PubMed=23580709;
RA Brown S.D., Utturkar S.M., Arkin A.P., Deutschbauer A.M., Elias D.A.,
RA Hazen T.C., Chakraborty R.;
RT "Draft Genome Sequence for Desulfovibrio africanus Strain PCS.";
RL Genome Announc. 1:E00144-13(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMG37807.1}.
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DR EMBL; AOSV01000013; EMG37807.1; -; Genomic_DNA.
DR RefSeq; WP_005985596.1; NZ_AOSV01000013.1.
DR AlphaFoldDB; M5PTY0; -.
DR PATRIC; fig|1262666.3.peg.1476; -.
DR OrthoDB; 5915071at2; -.
DR Proteomes; UP000011922; Unassembled WGS sequence.
DR GO; GO:0004332; F:fructose-bisphosphate aldolase activity; IEA:InterPro.
DR GO; GO:0016836; F:hydro-lyase activity; IEA:InterPro.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:InterPro.
DR CDD; cd00958; DhnA; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR HAMAP; MF_00960; ADH_synthase; 1.
DR InterPro; IPR010210; ADH_synthase.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002915; DeoC/FbaB/LacD_aldolase.
DR InterPro; IPR041720; FbaB-like.
DR NCBIfam; TIGR01949; ADH_synth; 1.
DR PANTHER; PTHR47916:SF1; 3-HYDROXY-5-PHOSPHONOOXYPENTANE-2,4-DIONE THIOLASE-RELATED; 1.
DR PANTHER; PTHR47916; FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 1; 1.
DR Pfam; PF01791; DeoC; 1.
DR PIRSF; PIRSF038992; Aldolase_Ia; 1.
DR SMART; SM01133; DeoC; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
FT ACT_SITE 151
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR038992-1"
FT ACT_SITE 182
FT /note="Schiff-base intermediate with dihydroxyacetone-P"
FT /evidence="ECO:0000256|PIRSR:PIRSR038992-1"
SQ SEQUENCE 275 AA; 29542 MW; F0A465CEE250F3EA CRC64;
MLASSNNIGK AIRLERIFNR NTERTIIVPL DHGVSVGPIS GLVDLRETVN HIVEGGANAV
LMHKGLIRCG HRGSGKDIGL ILHLSASTSL SPYPNAKTLV GTVEDAIRLG ADCVSVHVNL
GDETEARMLC DFGQVTSIAA QWGIPVLAMV YARGPKIRNQ YDKDVVKHCA RVGVELGADV
VKVCYTGNPD SFAEVTEACC VPVVIAGGEK MDNTRDIVQM VHDSVLAGGH GLSIGRNIFQ
AEDPRRLVAT LKGVVHEDWE VDEAMDFLNN TQKAS
//
