ID M5VT66_PRUPE Unreviewed; 1888 AA.
AC M5VT66;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
GN ORFNames=PRUPE_7G058100 {ECO:0000313|EMBL:ONH95228.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONH95228.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONH95228.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCA family.
CC CPR flippase (TC 3.A.1.211) subfamily. {ECO:0000256|ARBA:ARBA00008526}.
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DR EMBL; CM007657; ONH95228.1; -; Genomic_DNA.
DR RefSeq; XP_007203057.1; XM_007202995.1.
DR EnsemblPlants; ONH95228; ONH95228; PRUPE_7G058100.
DR GeneID; 18771352; -.
DR Gramene; ONH95228; ONH95228; PRUPE_7G058100.
DR KEGG; pper:18771352; -.
DR eggNOG; KOG0059; Eukaryota.
DR HOGENOM; CLU_000604_19_1_1; -.
DR OMA; WKNWIVL; -.
DR OrthoDB; 6951at2759; -.
DR Proteomes; UP000006882; Chromosome g7.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF263; ABC TRANSPORTER A FAMILY MEMBER 1; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 557..790
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1460..1698
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1888 AA; 209908 MW; 02F0225AC30F3962 CRC64;
MGTGRRQLKV MLWKNWLLKV RHPFVTCAEI LLPTVVMLLL IAIRMRVDTQ IHPSQPYIRK
GMFVEVGKGI SPNFEEVLEL LLNKEEFLAF APDTEETRSM INIISVKFPL LKNVSRVYKD
EQELETYIGS DLYGTCNQIM NCSNPKIKGA VVFHDQGPQS FDYSIRLNHT WAFSGFPDVK
SIMDTNGPYL NDLELGINTV PTMQYSFSGF LTLQQVLDSF IIFAAQQSDT KNIELTSSLP
SGEPSSLKVP WTSYGPSNIR IVPFPTREYT DDEFQSIIKS VMGVLYLLGF LYPISRLISY
SVFEKEQKIR EGLYMMGLED GIFHLSWFIA YALQFAVSSA IITVCTMDNL FKYSDKTVVF
IYFFFFGLSA IMLSFLISTF FTRAKTAVAV GTLTFLAAFF PYYSVNDEGV PLTLKVVASL
LSPTAFALGS INFADYERAH VGLRWSNIWR ASSGVNFLVC LLMMLLDALL YCLIGLYLDK
VLPRENGVRY PWNFIFHKRF WKNPSINKHL NHNSGVEVNS RDSVSKKASF SGKDNVKAAV
EAITFDMKQQ ELDHRCIKIR NLHKVYGSKK GKCCAVNSLQ LTMYENQILA LLGHNGAGKS
TTISMLVGLL RPTSGDALVF GKNIITEMEE IRKELGVCPQ NDILFPELTV REHLEIFAIL
KGVKEDFVNS AVVDMGDQVG LADKMNTSVN ALSGGMKRKL SLGIALIGNS KVIILDEPTS
GMDPYSMRLT WQLIKKIRKG RIVLLTTHSM DEAEVLGDRI AIMANGSLKC CGSSLFLKHK
YGVGYTLTLV KSAPTASVAA EIVFRHIPLA TCVSEVGTEI SFKLPLASSS SFESMFREIE
SCMKRPMSNL ETSSGEDYLG IESYGISVTT LEEVFLRVAG CDYVEAACFD QKTDLGLPDS
VVCQTTHDPV PKKIFHSKKS FGYYKEILGV LFTIVGRACG LIFAAVLSFL NFVGVQCCCC
GIISRSTFWR HSKALFIKRA ISARRDRKTI VFQLVIPAVF LFFGLLFLKL KPHPDQLSVT
FTTSHFNPLL RGGGGGPIPF DLSWPIAKEV AQYVEGGWIQ NFKPSAYKFP NAEKALDDAI
EAAGPTLGPV LLSMSEFLMS SFNESYQSRY GAIVMDDQND DGSLGYTVLH NSSCQHAAPT
YINLMNAAIL RLAAHNKNMT IQTRNHPLPM TKSQHLQHHD LDAFSAAVIV SIAFSFIPAS
FAVSIVKERE VKAKHQQLIS GVSILSYWAS TYIWDFISFL FPSSFAIILF YVFGLEQFIG
SGCLLSTVIM FLAYGLAIAS TTYCLTFFFS DHSMAQNVVL LVHFFTGLIL MVISFIMGLI
KTTSSANSFL KNFFRLSPGF CFADGLASLA LLRQDMKDKT SNEAFDWNVT GGSICYLGIE
SICYFLLTLG LEHLPYNKLT LATLKEWWKS IKSTRQGSSS YLEPLLKSSS EVITHDLDED
IDVKTERTRV LSGSIDNAII YLRNLWKVYP GGKLHGPKIA VNSLTFAVQE GECFGFLGTN
GAGKTTTLSM LTGEESPTDG TACIFGKDIC SNPKAARRHI GFCPQFDALL EFLTVQEHLE
LYATIKGVPD YQIDDVVTEK LVEFDLLKHA NKPSFSLSGG NKRKLSVAIA MIGDPPIVIL
DEPSTGMDPI AKRFMWEVIS RLSTRRGKTA VILTTHSMNE AQALCTRMGI MVGGRLRCIG
SPQHLKTRFG NHLELEVKPF EVSSGDLENL CRVIQERLSY VPSHPRSLLD GFEVCIGAID
SIVADNASVA EISLSREMII IIGRWLGNEE RIKSLISSVP LSDGVIGEQL AEQLVRDGGI
PLPIFSEWWL SNEKFSAIDS FVFSSFPGAI FQGFNGLSAK YQLPYGQGLS LADVFGHLER
NRYKLGIAEY SISQSTLETI FNHFAANS
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