ID M5WKR5_PRUPE Unreviewed; 944 AA.
AC M5WKR5;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=P-loop containing nucleoside triphosphate hydrolase, leucine-rich repeat domain, L {ECO:0008006|Google:ProtNLM};
GN ORFNames=PRUPE_4G285500 {ECO:0000313|EMBL:ONI14527.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONI14527.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONI14527.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
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DR EMBL; CM007654; ONI14527.1; -; Genomic_DNA.
DR RefSeq; XP_007212657.1; XM_007212595.1.
DR AlphaFoldDB; M5WKR5; -.
DR EnsemblPlants; ONI14527; ONI14527; PRUPE_4G285500.
DR GeneID; 18780280; -.
DR Gramene; ONI14527; ONI14527; PRUPE_4G285500.
DR KEGG; pper:18780280; -.
DR eggNOG; KOG4658; Eukaryota.
DR HOGENOM; CLU_000837_8_1_1; -.
DR OMA; LEMWIVI; -.
DR OrthoDB; 990669at2759; -.
DR Proteomes; UP000006882; Chromosome g4.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155:SF1156; DISEASE RESISTANCE PROTEIN RGA3; 1.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00369; LRR_TYP; 2.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 6..96
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 190..425
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 944 AA; 108050 MW; 9D04A4C56C5E3E00 CRC64;
MAGALISVLL ERLASTTYEY IEGGVKLVLN VKEDVEEFTG TLQVIQAVLE DAEQRQVTDQ
AVKIWLDKLK DISYQMVDVL DEWNTNILKQ QVEKQEREGD PNAHVTKKVR FFSFPRFSSF
PRFFCVGKVS DIAPKIKDLN DKLTEIYEER KKYQFLSKEL GIQQPQQPQR PQTASFVDIS
GIFGRENEKE VLIKILWNHS SAEGKGLLII PIVGMGGIGK TTLTQLAYND DRVKTRFELR
KWVCVSDPFD EIKIAKAIIG EKPPKSNELD YVLERMSTSI KNKKFLLVLD DVWTDDPKKW
EQLRVPLIQN GAKGSIILVT TRKHEVADMM RTTRNMINLG ELNDECCLSI FNHMAFWDRD
VHEFGDISKE IVKKCKGLPL AAKTLGSLMQ NKTKMGEWKE VLHSKIWDLE KVEQEVFQPL
FLSYNDLAPT IKCCLLYCAT FPKDYEFERD DLIQLWMAQD YVISKGNKEK GTTGDAVFDN
LVARSFFQDF KKDCDTGTII GCKMHDIVHD FVQFLTKNEC LIIDHGEETT SESKVFGDKV
RHLTLRYFPE GPLPLFISSY NCKNLRTLAT FDSRITTIKP NLILQLKCLR TLNLSFNPIE
ELPKEIGELI HLRHIDLSFN CILKILPDTI CGLYNLSTLR LVGCSNLTKL PENMGNLINL
KHLYVECCGF LESFPKVIGR LTSLQTLDVC PCGGDKDEAF QIGDLRNLNL EGSLQIRLQG
DATDKSEVEK AQLWDKKLFT LTVDLEGQTN SSSSSVEILN ALRPHPDLES LGILWHIGTT
WPNWIQSLHN LKFLTVGWGT SCELWPLGKL EHIERLALYR MEAVKKVGVE FLGLEDQTSF
RIRSPQIFPK LKQLCFYNMS NWEEWEGVEE WTKEDSKITI MPDLSELRIG GCKLLKALPD
FIFKTQLRTL DITKCRRLAE HYEEGSGERA KISAKIPNIR ISSG
//
