ID M5WRV7_PRUPE Unreviewed; 778 AA.
AC M5WRV7;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221};
GN ORFNames=PRUPE_6G036200 {ECO:0000313|EMBL:ONH99564.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONH99564.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONH99564.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361221}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361221}.
CC -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family.
CC {ECO:0000256|ARBA:ARBA00009476, ECO:0000256|RuleBase:RU361221}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU361221}.
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DR EMBL; CM007656; ONH99564.1; -; Genomic_DNA.
DR RefSeq; XP_007208356.1; XM_007208294.1.
DR AlphaFoldDB; M5WRV7; -.
DR STRING; 3760.M5WRV7; -.
DR EnsemblPlants; ONH99564; ONH99564; PRUPE_6G036200.
DR GeneID; 18773342; -.
DR Gramene; ONH99564; ONH99564; PRUPE_6G036200.
DR KEGG; pper:18773342; -.
DR eggNOG; KOG0475; Eukaryota.
DR HOGENOM; CLU_015263_3_1_1; -.
DR OMA; HDGRQSC; -.
DR OrthoDB; 388704at2759; -.
DR Proteomes; UP000006882; Chromosome g6.
DR GO; GO:0009507; C:chloroplast; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:UniProtKB-UniRule.
DR CDD; cd04592; CBS_pair_voltage-gated_CLC_euk_bac; 1.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF3; CHLORIDE CHANNEL PROTEIN CLC-F; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 2.
PE 3: Inferred from homology;
KW Chloride {ECO:0000256|RuleBase:RU361221};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|RuleBase:RU361221};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361221};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361221};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361221}; Transport {ECO:0000256|RuleBase:RU361221}.
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 274..300
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 312..334
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 354..377
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 389..411
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 431..450
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 462..482
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 502..526
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
SQ SEQUENCE 778 AA; 83126 MW; 05AA480D7C8BE258 CRC64;
MSGEDEALLL RSSNDINKDE NGGASAENGS DLEAQDGMSS RKNSISPTSR RGGIGGFKDL
LIKHLDGAGG LSGRRLSFKR GRENHNHREI REPRSPVDPH HQHHNHQQHH EPLAGMDGND
ELADSAPPEW ALLLIGCLLG LATGLFVAAF NKGVHVIHEW AWAGTPNDGA AWLRLQRLGD
TWHRILLIPV TGGVIVGMMH GLLEILDQIT QSSSSQRQGF DLLAGVFPTI KAVQAAVTLG
TGCSLGPEGP SVDIGKSCAN GFSLMMENNR ERKIALVAAG AAAGISSGFN AAVAGCFFAI
ETVLRPLRAE NSPPFTTAMI ILASVISSTV SNVLLGTQSA FTVPAYDLKS AAELPLYLIL
GMLCGAVSVA FTRLVAWFTK FFDFIKEKLG LPAVACPALG GLGAGIIALK YPGILYWGFT
NVEEILHTGR IASAPGIWLL TQLAAAKVVA TALCKGSGLV GGLYAPSLMI GAAVGAVFGG
SAAELINSAI PGNAAVAQPQ AYALVGMAAT LASVCSVPLT SVLLLFELTK DYRILLPLMG
AVGLAIWVPS VVNQPMETEP SDTRNSARVY SVVSAAEERD EVMRRQLDSG HDLELSVIGN
TSDSKTVSEE LLLEDLKVSQ AMSKNYVKVP VSVTMKEAIK CMRDNHQNCV LVVDDEDLLE
GILTFGDVRR FQSKKSSDTS KSDCGFLDAN TCLVSSVCTR GISYCGRARG IFTCYPDTDL
AMAKELMEAK DIRQLPVVKR VREPSKEIKR RIVAILHYSS ILNCLREEIK SREISQST
//
