ID M5XAT5_PRUPE Unreviewed; 813 AA.
AC M5XAT5;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Histidine kinase/HSP90-like ATPase domain-containing protein {ECO:0000259|SMART:SM00387};
GN ORFNames=PRUPE_3G201400 {ECO:0000313|EMBL:ONI18181.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONI18181.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONI18181.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- SIMILARITY: Belongs to the heat shock protein 90 family.
CC {ECO:0000256|ARBA:ARBA00008239}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM007653; ONI18181.1; -; Genomic_DNA.
DR RefSeq; XP_007214966.1; XM_007214904.1.
DR AlphaFoldDB; M5XAT5; -.
DR STRING; 3760.M5XAT5; -.
DR EnsemblPlants; ONI18181; ONI18181; PRUPE_3G201400.
DR GeneID; 18783030; -.
DR Gramene; ONI18181; ONI18181; PRUPE_3G201400.
DR KEGG; pper:18783030; -.
DR eggNOG; KOG0019; Eukaryota.
DR HOGENOM; CLU_006684_1_3_1; -.
DR OMA; KWKLMNE; -.
DR OrthoDB; 547579at2759; -.
DR Proteomes; UP000006882; Chromosome g3.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; IEA:EnsemblPlants.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0032991; C:protein-containing complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR GO; GO:0034605; P:cellular response to heat; IBA:GO_Central.
DR GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR GO; GO:0050821; P:protein stabilization; IBA:GO_Central.
DR CDD; cd16927; HATPase_Hsp90-like; 1.
DR Gene3D; 3.30.230.80; -; 1.
DR Gene3D; 3.40.50.11260; -; 1.
DR Gene3D; 1.20.120.790; Heat shock protein 90, C-terminal domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR HAMAP; MF_00505; HSP90; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR019805; Heat_shock_protein_90_CS.
DR InterPro; IPR037196; HSP90_C.
DR InterPro; IPR001404; Hsp90_fam.
DR InterPro; IPR020575; Hsp90_N.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR PANTHER; PTHR11528; HEAT SHOCK PROTEIN 90 FAMILY MEMBER; 1.
DR PANTHER; PTHR11528:SF41; HEAT SHOCK PROTEIN 90-6, MITOCHONDRIAL; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR Pfam; PF00183; HSP90; 1.
DR PIRSF; PIRSF002583; Hsp90; 1.
DR PRINTS; PR00775; HEATSHOCK90.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF110942; HSP90 C-terminal domain; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00298; HSP90; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882}.
FT DOMAIN 114..276
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|SMART:SM00387"
SQ SEQUENCE 813 AA; 91810 MW; 54C1EEA62C9B95EE CRC64;
MHRLPRRSVS AILRHGGARH RTTAAPISCA STHLGSVGET DAKVRWHSAL ASGKFNPCKP
TAQFASNNGL CFGNRFESTA AASDASAEPP AERFEYQAEV NRLMDLIVNS LYSNKEVFLR
ELISNASDAL DKLRFLSVTE PDLLKGGGDL DIRIQTDKDN GIIHIIDSGI GMTRQELVDC
LGTIAQSGTA KFSKLLKDSK DAGGDNNLIG QFGVGFYSAF LVADRVVVST KSPKSDKQYV
WQGEANASSY TIQEETDPEK LIPRGTRLSL YLKRDDKGFA VPERIQKLVK NYSQFVSFPI
YTWQEKGYTK EVEVDEDPAE SKKDGENEKT EVQKKKTKTV VEKYWDWELT NETQPIWLRN
PKEVTTEDYN EFYKKTFNEY LDPLASSHFT TEGEVEFRSI LYVPAVAPRG KDDIVNSKTK
NISLYVKRVF ISDDFDGELF PRYLSFVKGV VDSNDLPLNV SREILQESRI VRIMRKRLVR
KAFDMILGIS MSEDRADYEK FFENFGKHLK LGCIEDRENH KRIAPLLRFF SSQSEDVMIS
LDEYLENMKP EQKGIYYIAS DSVESASNTP FLEKLLEKNF EVLYLVDPID EVAIQNLESY
KEKKFLDISK EDLDLGDKNE EKEKEIKQEY GQTCDWIKKR LGDKVASVQI SNRLSSSPCV
LVSGKFGWSA NMERLMKAQT VGDTSSLEFM RGRRVFEINP EHPIIQNLNA ASKINPDDED
AIRAIDLLYD TALVSSGFTP ENPAQLGGKI YEMMGLALSG KWSTPVAEVQ QPGRQHHNPE
TLEAEVQHPG TPHHNTKILE AEVVEPVEAG TQK
//
