ID M6D5N6_9LEPT Unreviewed; 344 AA.
AC M6D5N6;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=UDP-glucose 4-epimerase {ECO:0000256|ARBA:ARBA00018569};
DE EC=5.1.3.2 {ECO:0000256|ARBA:ARBA00013189};
DE AltName: Full=UDP-galactose 4-epimerase {ECO:0000256|ARBA:ARBA00031367};
GN Name=capD {ECO:0000313|EMBL:EMJ96548.1};
GN ORFNames=LEP1GSC194_0256 {ECO:0000313|EMBL:EMJ96548.1};
OS Leptospira alstonii serovar Sichuan str. 79601.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1218565 {ECO:0000313|EMBL:EMJ96548.1, ECO:0000313|Proteomes:UP000011988};
RN [1] {ECO:0000313|EMBL:EMJ96548.1, ECO:0000313|Proteomes:UP000011988}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=79601 {ECO:0000313|EMBL:EMJ96548.1,
RC ECO:0000313|Proteomes:UP000011988};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Galloway R.L., Vinetz J.M., Sutton G.G.,
RA Nierman W.C., Fouts D.E.;
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMJ96548.1}.
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DR EMBL; ANIK01000017; EMJ96548.1; -; Genomic_DNA.
DR RefSeq; WP_020772548.1; NZ_ANIK01000017.1.
DR AlphaFoldDB; M6D5N6; -.
DR PATRIC; fig|1218565.3.peg.1065; -.
DR OrthoDB; 9803111at2; -.
DR Proteomes; UP000011988; Unassembled WGS sequence.
DR GO; GO:0003978; F:UDP-glucose 4-epimerase activity; IEA:InterPro.
DR GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013692; CapD_C.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR PANTHER; PTHR43318:SF2; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE (INVERTING); 1.
DR Pfam; PF08485; Polysacc_syn_2C; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000313|EMBL:EMJ96548.1}.
FT DOMAIN 7..282
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
FT DOMAIN 285..332
FT /note="UDP-glucose 4-epimerase CapD C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08485"
SQ SEQUENCE 344 AA; 38845 MW; 5D592AD40E8B6BD2 CRC64;
MFKNKSLLIT GGTGSFGKAV LDRFLNSDIK EIRIFSRDEK KQDDLRKRYN NSKLKFFIGD
VRDLDSVRSA FRGVDYVFHA AALKQVPSCE FHPLEAVKTN VLGTENVIEA AIQSNVKKIV
CLSTDKAVYP INAMGISKAM MEKVMVAKSR SIENSDMVVC GTRYGNVMAS RGSVIPLFIE
QIKNNKPITI TDPNMTRFMM SLEDAVELVL YAFQNGHNGD IFVQKAPAAT IETLSKALLE
LFDNVNYPVE IIGTRHGEKL YETLLSREEM ASAEDMTDYY RIPPDLRDLN YGKFIDQGEK
KISSLEDYNS HNTERLNLAG MKEMLLKLQF IRNIIEGKPA EIID
//
