ID   M6FN37_9LEPT            Unreviewed;       654 AA.
AC   M6FN37;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Adenylate/guanylate cyclase catalytic domain protein {ECO:0000313|EMBL:EMK24186.1};
GN   ORFNames=LEP1GSC008_0067 {ECO:0000313|EMBL:EMK24186.1};
OS   Leptospira kirschneri serovar Bulgarica str. Nikolaevo.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=1240687 {ECO:0000313|EMBL:EMK24186.1, ECO:0000313|Proteomes:UP000011980};
RN   [1] {ECO:0000313|EMBL:EMK24186.1, ECO:0000313|Proteomes:UP000011980}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nikolaevo {ECO:0000313|EMBL:EMK24186.1,
RC   ECO:0000313|Proteomes:UP000011980};
RA   Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA   Sanka R., DePew J., Purushe J., Galloway R.L., Vinetz J.M., Sutton G.G.,
RA   Nierman W.C., Fouts D.E.;
RL   Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMK24186.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ANCE01000107; EMK24186.1; -; Genomic_DNA.
DR   AlphaFoldDB; M6FN37; -.
DR   PATRIC; fig|1240687.3.peg.2286; -.
DR   Proteomes; UP000011980; Unassembled WGS sequence.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR045983; GUC-dom-containing_N.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF19363; DUF5939; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
FT   DOMAIN          483..597
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   654 AA;  75770 MW;  BD510957E01A780A CRC64;
     MWILFQRIGK HRNTKIGKYR TYMEINQSKI KASEISDLTD FLNRYPWTEE WERFGKTIDT
     LWEFELDENV ETLWPWLIDT SSFNKRIGIP EMKFVEKEGK LFGRSKNAGI LMEWEEVPWE
     WEYCKGINNA RIYSRGLARY VRTRYVLEKL SKEKTKLTVY FGWVPRGIVG KLILPYGMKQ
     MYQEYQKGLA GLLQDIETRR KNEATLLLNQ NSKQTSPITE SLKLKQIKTN LLREGIDEGL
     LDRVIHYILS EDENELYRIR IKKLAMEWKI PVESLLLLFL HGCRQGLFTL SWDVICPHCR
     GVRSELFNLG DIPTQDSCDV CGIDFESTKV NSIEVTFHVH PSIREVQKRF FCAAEPSTKT
     HIRFQRTIQP GSEYITNLLL TEGVYRLRIA GEKKYNLLEL QPSPTESIRW TVDQAAEELT
     AKPMPTVQIF NAENSPRTFI IEERKEDAIG LRPVELFNFQ DFRDLFSEQA IASDLQLDIG
     VQTILFTDIV GSTRFYLTEG DNGAFKEVRE HFVQVFRIIK EHKGAVVKTI GDSVMASFSS
     PLDSLLASIE LQKVFQVTPE NRIQIRISIH SGQCLAVNLN SNIDYFGNTV NYASKLQAIT
     DAGEIAFSEA IFRDEEIRNH LKTSGMKVKK VPFKLPWSQA EDSTYKLVQE VSKN
//