ID M7AQ90_CHEMY Unreviewed; 576 AA.
AC M7AQ90;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=ER membrane protein complex subunit 7 {ECO:0000256|ARBA:ARBA00020825};
GN ORFNames=UY3_16169 {ECO:0000313|EMBL:EMP26769.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP26769.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
CC -!- SUBUNIT: Component of the ER membrane protein complex (EMC).
CC {ECO:0000256|ARBA:ARBA00011276}.
CC -!- SIMILARITY: Belongs to the EMC7 family.
CC {ECO:0000256|ARBA:ARBA00008880}.
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DR EMBL; KB576442; EMP26769.1; -; Genomic_DNA.
DR AlphaFoldDB; M7AQ90; -.
DR STRING; 8469.M7AQ90; -.
DR eggNOG; KOG2579; Eukaryota.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR CDD; cd00087; FReD; 1.
DR Gene3D; 3.90.215.10; Gamma Fibrinogen, chain A, domain 1; 1.
DR InterPro; IPR039163; EMC7.
DR InterPro; IPR019008; EMC7_beta_sandwich.
DR InterPro; IPR036056; Fibrinogen-like_C.
DR InterPro; IPR014716; Fibrinogen_a/b/g_C_1.
DR InterPro; IPR002181; Fibrinogen_a/b/g_C_dom.
DR PANTHER; PTHR13605:SF4; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7; 1.
DR PANTHER; PTHR13605; UNCHARACTERIZED; 1.
DR Pfam; PF09430; EMC7_beta-sandw; 1.
DR Pfam; PF00147; Fibrinogen_C; 1.
DR SMART; SM00186; FBG; 1.
DR SUPFAM; SSF56496; Fibrinogen C-terminal domain-like; 1.
DR PROSITE; PS51406; FIBRINOGEN_C_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 341..560
FT /note="Fibrinogen C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51406"
FT REGION 47..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 224..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 576 AA; 65643 MW; 13D0DEA0FA8E0C58 CRC64;
MPGRALKGSD DDIPGVTTTL CEYPCPVQEP HQPHTHLTPA KERQHFRLGN PHGQSFHPSR
ATPPPRDSQD GFVLSGVSLA HALTDGSFVV HDIPSGSYVV EVISPAYRFE PVRVDITSKG
KMRARYVNYI KTSEVVRLPY PLQMKSSGPP SYFIKRESWG WTDFLMNPMV MMMVLPLLIF
VLLPKVVNTS DPDMRREMEQ SMNMLNSNHE LPDVSEFMTR LFSSKSSSKS GSGSSKAGKS
GAGKRSRCRF SESSEDPLNQ MTERSLSVSL RSTQVLQRPE KSKCASLQRD RLRRKMNLKS
SVGFILLLLF KCAAWTSAEE AVMLANAHLL PPGGYQRLSN NNEKEYARDC YEIFQHSEGS
AKDGLYVIQP MKDPIVAYCN MEDGGWTVIQ HITANSTVDF DRIWHDYKYG FGSVHDNYWL
GNEYVYQLTN TSRPYTLRVK LVDLNAEIKW GEYEPFKIED EESQYRIRLG LYKGNAADAL
TQDTEAYLHD NQKFTTKDRD NDNYFQNCAK LEYNGIPGGG WWYDSCAGAN LNRRNVIYWQ
KDCNKEHLCK FAWMMVKPTD HGQCPNKACR CEKDEL
//
