ID M7AV26_CHEMY Unreviewed; 376 AA.
AC M7AV26;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Calumenin {ECO:0000256|ARBA:ARBA00014000};
GN ORFNames=UY3_14308 {ECO:0000313|EMBL:EMP28594.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP28594.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the CREC family.
CC {ECO:0000256|ARBA:ARBA00006431}.
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DR EMBL; KB562234; EMP28594.1; -; Genomic_DNA.
DR AlphaFoldDB; M7AV26; -.
DR STRING; 8469.M7AV26; -.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
DR GO; GO:0033018; C:sarcoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 4.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR10827:SF76; CALUMENIN; 1.
DR PANTHER; PTHR10827; RETICULOCALBIN; 1.
DR Pfam; PF13202; EF-hand_5; 2.
DR Pfam; PF13499; EF-hand_7; 2.
DR Pfam; PF13833; EF-hand_8; 1.
DR SMART; SM00054; EFh; 6.
DR SUPFAM; SSF47473; EF-hand; 2.
DR PROSITE; PS00018; EF_HAND_1; 5.
DR PROSITE; PS50222; EF_HAND_2; 6.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..376
FT /note="Calumenin"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004079649"
FT DOMAIN 68..103
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 129..164
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 165..200
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 212..247
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 249..284
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 326..361
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 376 AA; 44639 MW; 1967ACD1D6066677 CRC64;
MTIQQFLVYL SLCAVCVLTK PTDKKDRVHH DPQLSDKVHD DAQNFEYDHD AFLGADEAKT
FDQLTPEESK ERLGKIVSKI DEDKDGFVTV EELRDWIKFA QKRWIYEDVE RQWKGHDLNE
DGLISWEEYK NATYGYILDK IDTDKDGFVT EGELKAWIKK AQKKYVYDNV ERQWQEFDMN
QDGLISWDEY RNVTYGTYLD DPDPDDGFNY KQMMMRDERR FKMADKDGDL IATKEEFTAF
LHPEEYDYMK DIVVQETMED IDKNRDGVID LEEYIGDMYS HDGDADEPEW VKTEREQFVE
FRDKNRDGKM DKEETKDWIL PSDYDHAEAE ARHLVYESDQ NKDGKLTKEE IVDKYDLFVG
SQATDFGEAL VRHDEF
//
