ID M7CB96_CHEMY Unreviewed; 414 AA.
AC M7CB96;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Kynureninase {ECO:0000313|EMBL:EMP37957.1};
GN ORFNames=UY3_04849 {ECO:0000313|EMBL:EMP37957.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP37957.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
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DR EMBL; KB520916; EMP37957.1; -; Genomic_DNA.
DR AlphaFoldDB; M7CB96; -.
DR STRING; 8469.M7CB96; -.
DR eggNOG; KOG3846; Eukaryota.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0030429; F:kynureninase activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
DR GO; GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR010111; Kynureninase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR NCBIfam; TIGR01814; kynureninase; 1.
DR PANTHER; PTHR14084; KYNURENINASE; 1.
DR PANTHER; PTHR14084:SF0; KYNURENINASE; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Pyridine nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022642};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443}.
FT DOMAIN 118..276
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
SQ SEQUENCE 414 AA; 45540 MW; 4485D9939FBDDC7B CRC64;
MDPSSHGFPV TVLEQTASQL GCNPADQKLA LHLDEEDELK HLRECFHIPK VKDLPPTDST
LVNENESCIY FAGNSLGLQP KKVKAYLDEE LDMWARRGVH GHFSGKRPWA LGDECIVELM
ADIVGARKEE VALMNGLTVN LHLQMLSFFS PTPSRYKILL EAKAFPSDHY AVESQLRLHG
LDVEKCMLMV QPRKGEETLR IKDILDIIEK EGDSVAVILL SGVQYYTGQL FDIPRITKAG
QEKGCYVGFD LAHAVGNVEL HLHDWGVDFA CWCSYKDPHQ GPWHPLQHTD LRPCHTLCSP
PSKGPVVPCS ATSLSGYCRE LSGHFLMAPT SSLPLLQGLI LQTPAPIQEL SLGPPVPSSS
TALSRVLAVL SAFQGHSPST LGRELSFSAL PFCMGLLGCS LQSFSDWLTP VQSP
//
