ID M7NRB1_PNEMU Unreviewed; 732 AA.
AC M7NRB1;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=PNEG_01961 {ECO:0000313|EMBL:EMR09777.1};
OS Pneumocystis murina (strain B123) (Mouse pneumocystis pneumonia agent)
OS (Pneumocystis carinii f. sp. muris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX NCBI_TaxID=1069680 {ECO:0000313|EMBL:EMR09777.1, ECO:0000313|Proteomes:UP000011958};
RN [1] {ECO:0000313|Proteomes:UP000011958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B123 {ECO:0000313|Proteomes:UP000011958};
RX PubMed=26899007; DOI=10.1038/ncomms10740;
RA Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT "Genome analysis of three Pneumocystis species reveals adaptation
RT mechanisms to life exclusively in mammalian hosts.";
RL Nat. Commun. 7:10740-10740(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMR09777.1}.
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DR EMBL; AFWA02000009; EMR09777.1; -; Genomic_DNA.
DR RefSeq; XP_007873938.1; XM_007875747.1.
DR AlphaFoldDB; M7NRB1; -.
DR STRING; 1069680.M7NRB1; -.
DR GeneID; 19895655; -.
DR VEuPathDB; FungiDB:PNEG_01961; -.
DR eggNOG; KOG0800; Eukaryota.
DR HOGENOM; CLU_378604_0_0_1; -.
DR OrthoDB; 2730740at2759; -.
DR Proteomes; UP000011958; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16461; RING-H2_EL5-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45969:SF69; OS07G0686300 PROTEIN; 1.
DR PANTHER; PTHR45969; RING ZINC FINGER PROTEIN-RELATED; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000011958};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 659..702
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 22..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 76..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 543..575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 703..732
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 732 AA; 80642 MW; 3FE482E680269C03 CRC64;
MGQASSFQNR RQENILERTE TANATHTGHH HNTTIADTLS SSVDNTEQND TEGLSSNGNA
SRASRFRRHL TAFSRLGGLS PNRHHTSSSV SRIPYSIGNR RRSMFGSSIP RRNTVFELPQ
THFSISSNQL TTTEYLDLHT LNRGDYTFTV RDLPLVDMSG IENYIPERPV SESSVNNDHQ
LFRGIIRRSQ RNTLSRNTRR ALEISGRIRT NNDAIMQHSF NGSGLNAISL RPGEDQAAVL
SRLLSVAAAA TAASLVGNNE QAIAEAQDIA MSQNPTNDRD SHVVDGSFEG FLRALQNGRL
AAALRNGGSE NGGGIPNENE ENSSIQPLNF FRMFRFGNSQ GSTQEGEDDP QNPRLVPIII
VGIRSVPPRD ITSPGTQHTS PFFDTLANLS VNMPLNYETS YQRDTEEREA NEQGVFSSNS
PIHSISMSER PISSSMNIVD ENLSNNEGIV NNLEPSRPSS ISASIFQNLG STDQISRYDT
NIHSSMPSGE SSIQHHNSFH IGSSFTQRHS NLNEHVSENA NLNNNNTSEL NINSIERVDN
NNASRINSNI NGTSRNDNSR SDRSSTTRSG SSNIDNRHNS TRSWIIYVLG GSYPEDHPIL
TTPSLFTDSP TYEDMLLLSS LIGPAKSPVA TKDEIESAGG LHVLSVNSSS ADIYLEERCV
ICLNNYEIGE ECRQLNKCKH FFHKACIDEW LMTGRNTCPT CRAEGVNSRK NKSPTSNITS
EQSSTNIPMT GV
//
