ID M7NVK2_PNEMU Unreviewed; 343 AA.
AC M7NVK2;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
GN ORFNames=PNEG_00346 {ECO:0000313|EMBL:EMR11317.1};
OS Pneumocystis murina (strain B123) (Mouse pneumocystis pneumonia agent)
OS (Pneumocystis carinii f. sp. muris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX NCBI_TaxID=1069680 {ECO:0000313|EMBL:EMR11317.1, ECO:0000313|Proteomes:UP000011958};
RN [1] {ECO:0000313|Proteomes:UP000011958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B123 {ECO:0000313|Proteomes:UP000011958};
RX PubMed=26899007; DOI=10.1038/ncomms10740;
RA Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT "Genome analysis of three Pneumocystis species reveals adaptation
RT mechanisms to life exclusively in mammalian hosts.";
RL Nat. Commun. 7:10740-10740(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMR11317.1}.
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DR EMBL; AFWA02000001; EMR11317.1; -; Genomic_DNA.
DR RefSeq; XP_007872219.1; XM_007874028.1.
DR AlphaFoldDB; M7NVK2; -.
DR STRING; 1069680.M7NVK2; -.
DR GeneID; 19894044; -.
DR VEuPathDB; FungiDB:PNEG_00346; -.
DR eggNOG; KOG0153; Eukaryota.
DR HOGENOM; CLU_027112_0_0_1; -.
DR OMA; CPLRVQW; -.
DR OrthoDB; 929875at2759; -.
DR Proteomes; UP000011958; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12265; RRM_SLT11; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR039171; Cwc2/Slt11.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR034356; Slt11_RRM.
DR InterPro; IPR048995; STL11/RBM22-like_N.
DR PANTHER; PTHR14089; PRE-MRNA-SPLICING FACTOR RBM22; 1.
DR PANTHER; PTHR14089:SF6; PRE-MRNA-SPLICING FACTOR RBM22; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF21369; STL11_N; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011958};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 200..274
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 343 AA; 38718 MW; C93712C7AC2C8B59 CRC64;
MPPKLDINKS GWESAEFPAI CESCLGPNPY VRMTKREYGK ECKICTRPFT VFSWHPGKES
RYKKTEICLT CSRIKNCCQN CLLDLQFGLP IQVRDAALKL VNQGPQSDIN REYYAQNNEG
KWKDGNTPCE FGKVDSAARE LLKKLARSEP YYKKQIHMAK NPELSNISNH STDSSAPVFG
RSISHITSNQ LVPPQDKKIT SLFIIGIEDD LPEHAIRVYF EKYGPIKSLV CSHRSRCAFV
NFTTRVAAET AAKACRNGDI LINGCPLKVQ WGRPRPLGGY NQEQQNAKMS RFVMSQSQFA
TQNPGEESHA TSEIKKPEDT VLELPPGQDG DIAYQSMHPY YQT
//
