ID M7UN95_BOTF1 Unreviewed; 1846 AA.
AC M7UN95;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Putative kinesin heavy chain protein {ECO:0000313|EMBL:EMR88348.1};
GN ORFNames=BcDW1_2971 {ECO:0000313|EMBL:EMR88348.1};
OS Botryotinia fuckeliana (strain BcDW1) (Noble rot fungus) (Botrytis
OS cinerea).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Botrytis.
OX NCBI_TaxID=1290391 {ECO:0000313|EMBL:EMR88348.1, ECO:0000313|Proteomes:UP000012045};
RN [1] {ECO:0000313|Proteomes:UP000012045}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BcDW1 {ECO:0000313|Proteomes:UP000012045};
RX PubMed=23704180; DOI=10.1128/genomea.00252-13;
RA Blanco-Ulate B., Allen G., Powell A.L., Cantu D.;
RT "Draft genome sequence of Botrytis cinerea BcDW1, inoculum for noble rot of
RT grape berries.";
RL Genome Announc. 1:E0025213-E0025213(2013).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR EMBL; KB707787; EMR88348.1; -; Genomic_DNA.
DR STRING; 1290391.M7UN95; -.
DR HOGENOM; CLU_001485_20_2_1; -.
DR Proteomes; UP000012045; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd22705; FHA_KIF1; 1.
DR CDD; cd01365; KISc_KIF1A_KIF1B; 1.
DR CDD; cd22249; UDM1_RNF168_RNF169-like; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.250.2520; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR InterPro; IPR032405; Kinesin_assoc.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF3; KINESIN FAMILY MEMBER 14-LIKE; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF12473; DUF3694; 1.
DR Pfam; PF12423; KIF1B; 1.
DR Pfam; PF00225; Kinesin; 1.
DR Pfam; PF16183; Kinesin_assoc; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}.
FT DOMAIN 8..365
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT DOMAIN 1628..1801
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1496..1517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1545..1613
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1692..1716
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1804..1846
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 436..474
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 758..835
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1499..1517
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1557..1605
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1696..1716
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 111..118
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1846 AA; 204235 MW; 7A5D30C882E6FB96 CRC64;
MAPGGGGNIK VVVRCRPFNS REIDRGAKCI VQMKDAQTVI TPPEGHEAKS RDAKGGKADT
GQKVFAFDRS YWSFDKNDPS YAGQDNLHTD LGKPLLDNAF QGYNNCIFAY GQTGSGKSYS
MMGYGKDAGV IPKICQDMFE RIGELQQDKH LKCTVEVSYL EIYNERVRDL LNPSTKGNLK
VREHPSTGPY VEDLAKLVVS SFQEIENLMD EGNKARTVAA TNMNETSSRS HAVFTLTLTQ
KRLDVETKMA MEKVAKISLV DLAGSERANS TGATGARLKE GAEINRSLST LGRVIAALAD
LSEGKKKKVG KGNQVPYRDS VLTWLLKDSL GGNSMTAMIA AISPADINFD ETLSTLRYAD
SAKRIKNHAV VNEDANARMI RELKEELAQL RGKLTGGGGG GGGGGPADEI YAEGTPLEKQ
MVTIVSSDGA VKKVSKAEIT EQLNQSEKLY SDLNQTWEEK LQKTEEIHKE REAALEELGI
SIEKGFVGLH TPKKMPHLVN LSDDPLLAEC LVYNLKPGST SVGNVDTNAA HAAEIRLNGT
RILHEHCTFE NVDNVVTLTP TEGAAVMVNG QRVEKPTRLR SGFRVILGDF HIFRFNNPTE
ARAERAEQSL LRHSVTANQL ENFKDWDKFS PSSTPRPAHD RTFSKAISDL DFDGSSRADS
PVPGRGLSDW SLARREAAGA ILGTDQKIAG LSDEELNVLF EDVQRARAER ATANLEDDLD
SVTSYPMREK YLSNGTLDNF SLDTALTMPS TPKQGEVEDR MREVKEEMQV QLEKQREEFQ
EQLEIAKTSN VEVEEIKKEK VRMEETLREV KEEMLKQLEV QRKEYEEKLQ ELSPVKSGPD
GPPPLSEKEI VVAEKVAKHW QGRRYVRMAE AVFQNAAILK EAQIMSHEMD ENVVFQFAVV
DIGHALCSSY DMVLNDIEGD DFHLEDATKP CIGVRVIDYR NNVAHLWSLD KLQDRIRKMR
QMHQYLDRPE YLQHFRLDNP FMETCMPQYT HVGDVDVPLS AVFESRVQDF TLDVLSPFTM
HAIGIIKLSL EPSSAKAPSN TLKFNVVMHE MIGFAEREGT EVHGQLFIPP ASNEGGVTTT
QMIKDFDEGP IRFESVHSMS VPMFGPTDVS LRVAIFAKVS SMHLDKLLSW DDMRDNIPQP
KKKRKGARIA ESQFYSEEKH DVFAKVQILE LAESGDYPAV EVIQTSELDQ GTFQLHQGLQ
RRIAVTLTHN SGDALPWSDV TGLRVGRIQL VDHIGKSPDL SSPSTPPLYL KLLSKPIVKA
NANGTSNVCI VGKWDSSAHE SLLLDRVTAD KYKVQMSLSW DVKSEKLSRL MTFNMDVCSQ
IMSRNYVRST SMFASLFQSV RIVHSMTSIY SISVRPVAVK RAGDLWRMNT SEDYVKGEEA
LTNWTPRGIS LVKDFISARR KRQRLAEIDA AQPLLRRIAS SPVPITIPAP SIPQVVELDP
ADIPLPVSPP ATTENFPSPL SIDEALPSSV DGNALGIHRD GQFNNEITEK IESAIDTGSI
PHDPSQEQEK PQNQSEYNPH QTALLQKFTK YFHLCRDPST TILTPTNIEP PINGSPAPSL
FHTTSFTSNT SRSNSPRPSN FSNSLHPSTA NSRQTSRSRQ TSPIPHAHPK PSIPQHLATI
SQIKKNPSVL KAGMLLVPSA DSTKWIRRFV ELRRPYLHIH AVAGPNSGEE VNVVGLRNAR
VDHSPEIAKL LRNERQGGSG NASRNSSPAS AGAQQSWSNN GIGGIYGYGG RGRSGSGMGM
GIMGYGGRGN GNANGNGNGE SRREIEETVF AVYGTNNTWL FRARSEREKV EWIWKIDQGY
FSGGGGRAGN GSGNNSRGRR DDGSGDSDDV DAEVDVDVDR EDYLAD
//
