ID M7WUY7_RHOT1 Unreviewed; 794 AA.
AC M7WUY7;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=RHTO_01322 {ECO:0000313|EMBL:EMS21675.1};
OS Rhodotorula toruloides (strain NP11) (Yeast) (Rhodosporidium toruloides).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Sporidiobolales; Sporidiobolaceae; Rhodotorula.
OX NCBI_TaxID=1130832 {ECO:0000313|EMBL:EMS21675.1, ECO:0000313|Proteomes:UP000016926};
RN [1] {ECO:0000313|EMBL:EMS21675.1, ECO:0000313|Proteomes:UP000016926}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NP11 {ECO:0000313|EMBL:EMS21675.1,
RC ECO:0000313|Proteomes:UP000016926};
RX PubMed=23047670; DOI=10.1038/ncomms2112;
RA Zhu Z., Zhang S., Liu H., Shen H., Lin X., Yang F., Zhou Y.J., Jin G.,
RA Ye M., Zou H., Zou H., Zhao Z.K.;
RT "A multi-omic map of the lipid-producing yeast Rhodosporidium toruloides.";
RL Nat. Commun. 3:1112-1112(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR EMBL; KB722654; EMS21675.1; -; Genomic_DNA.
DR RefSeq; XP_016272794.1; XM_016415004.1.
DR AlphaFoldDB; M7WUY7; -.
DR GeneID; 27365335; -.
DR eggNOG; KOG0922; Eukaryota.
DR HOGENOM; CLU_001832_5_10_1; -.
DR OrthoDB; 3682876at2759; -.
DR Proteomes; UP000016926; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF118; ATP-DEPENDENT RNA HELICASE DHX33; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:EMS21675.1};
KW Hydrolase {ECO:0000313|EMBL:EMS21675.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 134..338
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 363..543
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 276..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..48
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 794 AA; 87409 MW; 864AF026B828419A CRC64;
MSTATELPKF ITSPRDPPQP ETPPPATCRR RSSPLPPSSG PAPPTSPPRA RVAARTRFPS
ATASPHKLDS LKRPPPNGTA GSPAPPKKRK LVVFDEEAEQ EANEQQKRKA KEEAQRLRPE
REKLPVFQGK DAILKGIADN DTVIVLAETG SGKTTQIPQY ILRSDTPCSG PRIVCTQPRH
VAAISLAQRV SAECGTQTGG LVGYTVRFDN KTSRTTRLTY ATDGALLAEM LGDRDLEAYD
VVVLDEAHER SLRTNMLMGF LKDIQKRRKE RVRVWKAEQA KSKGKAKANG VVANGEADGK
KGTDERDPTE LKIVVMSATI DAKRFSDFFD RAPVLYVAGR QHKVKIHYAE EPQPDFLDAA
LKMVYQIHTR YPPGSILVFL PGQEEIEGLA ASIKSFLPSL QKEYPHAEEL LVTPLYAKLH
AAEQAKAFLP SPPRTRKVIL ATNIAETSVT IPGVKYVVDC GLAKEKRYHA GTGIDSLVTE
SISQSSAKQR AGRAGRETDG FCFRLYTEAT YNGLEKRSQP EIQRVSLTFA ILHLLASGQD
DVFKFSFMDP PDVESIKFAL LTLIGLNALD KRGKITPLGR QMAQLPLDPV YARVLAASFI
EGCPREMIDL VSLLGSKDQL LINTSSTRDA ANAARQKFVH RTGDHMMLFN ILRAYEELDG
KDERKQWCKD NFISFKAMSS VLDARKQLLE RAQRLKLGDP DASAGDEAEP VLNALIGGLF
ANTALRQEDG SYRHTMTKQL VAIHHSSTLH GKKAPAIIDD ELVLTTKTYA RGISSIEPSQ
IRSKAPSLFG SSLK
//
