ID M7XD01_RHOT1 Unreviewed; 330 AA.
AC M7XD01;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase {ECO:0000313|EMBL:EMS21664.1};
GN ORFNames=RHTO_01724 {ECO:0000313|EMBL:EMS21664.1};
OS Rhodotorula toruloides (strain NP11) (Yeast) (Rhodosporidium toruloides).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Sporidiobolales; Sporidiobolaceae; Rhodotorula.
OX NCBI_TaxID=1130832 {ECO:0000313|EMBL:EMS21664.1, ECO:0000313|Proteomes:UP000016926};
RN [1] {ECO:0000313|EMBL:EMS21664.1, ECO:0000313|Proteomes:UP000016926}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NP11 {ECO:0000313|EMBL:EMS21664.1,
RC ECO:0000313|Proteomes:UP000016926};
RX PubMed=23047670; DOI=10.1038/ncomms2112;
RA Zhu Z., Zhang S., Liu H., Shen H., Lin X., Yang F., Zhou Y.J., Jin G.,
RA Ye M., Zou H., Zou H., Zhao Z.K.;
RT "A multi-omic map of the lipid-producing yeast Rhodosporidium toruloides.";
RL Nat. Commun. 3:1112-1112(2012).
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DR EMBL; KB722655; EMS21664.1; -; Genomic_DNA.
DR RefSeq; XP_016272783.1; XM_016415405.1.
DR AlphaFoldDB; M7XD01; -.
DR GeneID; 27365737; -.
DR eggNOG; ENOG502QQV2; Eukaryota.
DR HOGENOM; CLU_058877_0_0_1; -.
DR OrthoDB; 5488137at2759; -.
DR Proteomes; UP000016926; Unassembled WGS sequence.
DR GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd03311; CIMS_C_terminal_like; 1.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR002629; Met_Synth_C/arc.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR PANTHER; PTHR43844; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR43844:SF2; SYNTHASE, VITAMIN-B12 INDEPENDENT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12060)-RELATED; 1.
DR Pfam; PF01717; Meth_synt_2; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:EMS21664.1};
KW Transferase {ECO:0000313|EMBL:EMS21664.1}.
FT DOMAIN 113..324
FT /note="Cobalamin-independent methionine synthase MetE C-
FT terminal/archaeal"
FT /evidence="ECO:0000259|Pfam:PF01717"
SQ SEQUENCE 330 AA; 37584 MW; 1A722295F4B4F5A9 CRC64;
MQQEVGIKAI TDGEFRRHMF FDGFHNNLDG MVVVPNPGRE LFKMYVPDVK GFFESHAAKP
ADTMICKAKL VRNKPMYRPE FEFLKMLVKP DEYHLRHGEH AFDRSVYPTE VEYFADLAKA
YREELADLYE AGCRNVQFDD PLLAYFCATS MLEGMKAEGI NPEKVLDQYI QLYNDCIRDA
PEDMTIGLHL CRGNFKDGMH FSEGGYEHVS KKIFNELNAH AYYLEYDTER AGGFEPLADL
PANKTVVLGL LTSKFPQLEK KEDLVKRIHE AADFVAKGSN QTREQALQRL CLSCQCGFAS
HAEGNPVTEE DVVAKLRLVV ETAKAVWSDV
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