ID   M7Y7Z7_TRIUA            Unreviewed;      1105 AA.
AC   M7Y7Z7;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 55.
DE   RecName: Full=methionine S-methyltransferase {ECO:0000256|PROSITE-ProRule:PRU00888};
DE            EC=2.1.1.12 {ECO:0000256|PROSITE-ProRule:PRU00888};
GN   ORFNames=TRIUR3_26576 {ECO:0000313|EMBL:EMS46083.1};
OS   Triticum urartu (Red wild einkorn) (Crithodium urartu).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4572 {ECO:0000313|EMBL:EMS46083.1};
RN   [1] {ECO:0000313|EMBL:EMS46083.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23535596; DOI=10.1038/nature11997;
RA   Ling H.Q., Zhao S., Liu D., Wang J., Sun H., Zhang C., Fan H., Li D.,
RA   Dong L., Tao Y., Gao C., Wu H., Li Y., Cui Y., Guo X., Zheng S., Wang B.,
RA   Yu K., Liang Q., Yang W., Lou X., Chen J., Feng M., Jian J., Zhang X.,
RA   Luo G., Jiang Y., Liu J., Wang Z., Sha Y., Zhang B., Wu H., Tang D.,
RA   Shen Q., Xue P., Zou S., Wang X., Liu X., Wang F., Yang Y., An X., Dong Z.,
RA   Zhang K., Zhang X., Luo M.C., Dvorak J., Tong Y., Wang J., Yang H., Li Z.,
RA   Wang D., Zhang A., Wang J.;
RT   "Draft genome of the wheat A-genome progenitor Triticum urartu.";
RL   Nature 496:87-90(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-methionine + S-adenosyl-L-methionine = S-adenosyl-L-
CC         homocysteine + S-methyl-L-methionine; Xref=Rhea:RHEA:13761,
CC         ChEBI:CHEBI:57844, ChEBI:CHEBI:57856, ChEBI:CHEBI:58252,
CC         ChEBI:CHEBI:59789; EC=2.1.1.12; Evidence={ECO:0000256|PROSITE-
CC         ProRule:PRU00888};
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. {ECO:0000256|PROSITE-ProRule:PRU00888}.
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DR   EMBL; KD278239; EMS46083.1; -; Genomic_DNA.
DR   AlphaFoldDB; M7Y7Z7; -.
DR   STRING; 4572.M7Y7Z7; -.
DR   eggNOG; ENOG502QS81; Eukaryota.
DR   OMA; CVQERGI; -.
DR   GO; GO:0030732; F:methionine S-methyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-UniRule.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR025779; Met_S-MeTrfase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR007848; Small_mtfrase_dom.
DR   PANTHER; PTHR47087; METHIONINE S-METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR47087:SF3; METHIONINE S-METHYLTRANSFERASE; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   Pfam; PF05175; MTS; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51555; SAM_MT12; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|PROSITE-ProRule:PRU00888,
KW   ECO:0000313|EMBL:EMS46083.1};
KW   S-adenosyl-L-methionine {ECO:0000256|PROSITE-ProRule:PRU00888};
KW   Transferase {ECO:0000256|PROSITE-ProRule:PRU00888,
KW   ECO:0000313|EMBL:EMS46083.1}.
FT   DOMAIN          118..169
FT                   /note="Methyltransferase small"
FT                   /evidence="ECO:0000259|Pfam:PF05175"
FT   DOMAIN          721..1089
FT                   /note="Aminotransferase class I/classII"
FT                   /evidence="ECO:0000259|Pfam:PF00155"
SQ   SEQUENCE   1105 AA;  122950 MW;  888D2795290E2D1C CRC64;
     MAAPASPGEG MDVEVEAFLA SSAASAYGAA EALLQRLDAP ASRAAARRLL GAVRRRFADP
     AAGQDCVRAF NFRIIPDDPH LQQQGFQQIT TIEMPGIFVP CSAAFYEGLG QQPDSIFRDK
     TVAELGCGNG WMSIALAQRW SPFKVYGLDI NPRAIKIARI NLYLNALDDD GLPIYDGERK
     TLLDRIEFHE SDLLSCCRDS KIELDCIVGC IPQVLDPNPE VMPNIKINNS SEEFLYSRCY
     YCAFQGVVED QFGLGLIARA VEEGIALIKP MGIMIFSMGG RPGQVLCERL FLRRGFRINN
     LWQSKLMQAA DTDLSDLVEI EENSPHQFEF FVDLGGDQPI SARTACAYMK SGGCVSHALS
     MYSCHLRQPD QGGEIINVEN FQVKKIFDFL KDGFPEVSSS LDLSFDDNSV ADEKISFLAY
     LASFLKENKS NPCEPPAGCL NFRNLVTGFM KAYHHIPLTP DNVVVFPSRA VAIENALQLF
     LPALAIVDKH LTRHLPKQWL TSSTIEERAD CTEAENIVTV IESPRKWDLL IEFIRKLKPQ
     VVVTGMAQFD AIRTAAFVNL LNVTKDVGSW LFLDISEHLE LSRVPSSNSV LRYLAGNTLP
     SHVAILCGLV KNQVYSDLEV AFTISEQAAF CEALSQTVEL LEGHTSVISQ QYYGCLLHQL
     LAFRICEPHA QQERRPALVL PQRMIGFSNS AISAIKEAEF SLPDSKESCV IHMDLDRSFL
     PIPSAVKASI FESFARQNIM DSETDVRSSI QRLLKRNYNY PVDSDSDIIY GSTSLALFNK
     LVRRCVQERG IFVFPLGTNG HYVSAAKFLN ANTLTIPTKS SSGFKIEPSA LEDTLNNKEP
     FSRAWVYISG PTINPSGFLY SAKEIEELLY ICARNAARVV IDTSFSGLEF QTDDWPFPGV
     QFPFNRWPCW DLEGCLDDMA GHVAPVYLLG ELSLELTIAG LKFGFLISKD RSSEYSFPIS
     SQPHSTLKYT FRKLLGLKYD LDEHFSNLIA EQRETLKGRA NHLMKTLENC GWDVVGCHGG
     ISMLAKPTAY IGKLFRVNCF EGTLNGCNIR EALLRSTGLC ISSSTWTGIT DYCRFNFALE
     SGEFKRAMDC ITRFKELVLG GSDES
//