ID M7YBW3_9BACT Unreviewed; 599 AA.
AC M7YBW3;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Penicillin-binding protein 2 (PBP-2) {ECO:0000313|EMBL:EMS34676.1};
GN ORFNames=C943_03363 {ECO:0000313|EMBL:EMS34676.1};
OS Mariniradius saccharolyticus AK6.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC Mariniradius.
OX NCBI_TaxID=1239962 {ECO:0000313|EMBL:EMS34676.1, ECO:0000313|Proteomes:UP000010953};
RN [1] {ECO:0000313|EMBL:EMS34676.1, ECO:0000313|Proteomes:UP000010953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK6 {ECO:0000313|EMBL:EMS34676.1,
RC ECO:0000313|Proteomes:UP000010953};
RA Vaidya B., Khatri I., Tanuku N.R.S., Subramanian S., Pinnaka A.;
RT "Genome assembly of Mariniradius saccharolyticus AK6.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMS34676.1}.
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DR EMBL; AMZY02000005; EMS34676.1; -; Genomic_DNA.
DR RefSeq; WP_008624253.1; NZ_AMZY02000005.1.
DR AlphaFoldDB; M7YBW3; -.
DR STRING; 1239962.C943_03363; -.
DR eggNOG; COG0768; Bacteria.
DR InParanoid; M7YBW3; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000010953; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010953};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 49..210
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 252..572
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 599 AA; 66562 MW; 4F2B5A3894AEF2A3 CRC64;
MNDQRPLVII IVIAIVGLVL LTKLFLIQVA DDSFLKKAES NAIQRVVDHP YRGLVYDRNG
KILVYNYPIF DLMVIPREFQ VKDTTRFCEI FKISKEYLKE TYTAARKYSP VKPSPLIKQI
STTDFARIQD YLIDYPGLFV MTRSVRSYPQ ASAANALGYI GEISGPQLEK DTTKYYRQGD
YVGLSGIEGY YENELRGVKG VKYKLVNVRG VDKGPFKNGE FDTASVAGKN LTSTLDLDLQ
QYGEMLMAGK RGSVVAIEPK TGEILAMISA PTYDPNLLTG AQFGANYLLL NRDQDKPLFN
RPIMAMYPPG SIFKIVQSLI GLQMGVLTPN TTFGCNRSLV ACHNHPNPVN LFGAIRNSCN
PYYHQAYRMM INREVSTNTF KDTEIGLNAW RESVLKFGLG GPLGIDMKNE KGGSIPSSKY
YDRVYGEGRW KYSTIYSLSI GQGEMLVTPL QMANLAAIFA NKGYYYPPHL IKAVDGDYEK
IPVQFRTKMD VGVDAHHFDL IQDAMAEAIY GTAARAAISD IQIAGKTGTA QNPQGEDHSV
FIAFAPKDDP KIAIAVYVEN AGWGGRAAAS TASLMIEKYI RGSITRLALE EYVLAGKFM
//
