ID M8A1H0_TRIUA Unreviewed; 436 AA.
AC M8A1H0;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Apyrase {ECO:0000313|EMBL:EMS65821.1};
GN ORFNames=TRIUR3_31023 {ECO:0000313|EMBL:EMS65821.1};
OS Triticum urartu (Red wild einkorn) (Crithodium urartu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4572 {ECO:0000313|EMBL:EMS65821.1};
RN [1] {ECO:0000313|EMBL:EMS65821.1, ECO:0000313|Proteomes:UP000015106}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. G1812 {ECO:0000313|Proteomes:UP000015106};
RX PubMed=23535596; DOI=10.1038/nature11997;
RA Ling H.Q., Zhao S., Liu D., Wang J., Sun H., Zhang C., Fan H., Li D.,
RA Dong L., Tao Y., Gao C., Wu H., Li Y., Cui Y., Guo X., Zheng S., Wang B.,
RA Yu K., Liang Q., Yang W., Lou X., Chen J., Feng M., Jian J., Zhang X.,
RA Luo G., Jiang Y., Liu J., Wang Z., Sha Y., Zhang B., Wu H., Tang D.,
RA Shen Q., Xue P., Zou S., Wang X., Liu X., Wang F., Yang Y., An X., Dong Z.,
RA Zhang K., Zhang X., Luo M.C., Dvorak J., Tong Y., Wang J., Yang H., Li Z.,
RA Wang D., Zhang A., Wang J.;
RT "Draft genome of the wheat A-genome progenitor Triticum urartu.";
RL Nature 496:87-90(2013).
RN [2] {ECO:0000313|EnsemblPlants:TuG1812S0000506600.01.T01}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2022) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC {ECO:0000256|ARBA:ARBA00009283, ECO:0000256|RuleBase:RU003833}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KD039156; EMS65821.1; -; Genomic_DNA.
DR AlphaFoldDB; M8A1H0; -.
DR STRING; 4572.M8A1H0; -.
DR EnsemblPlants; TuG1812S0000506600.01.T01; TuG1812S0000506600.01.T01; TuG1812S0000506600.01.
DR Gramene; TuG1812S0000506600.01.T01; TuG1812S0000506600.01.T01; TuG1812S0000506600.01.
DR eggNOG; KOG1385; Eukaryota.
DR OMA; HFANAPQ; -.
DR OrthoDB; 757383at2759; -.
DR Proteomes; UP000015106; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR InterPro; IPR000407; GDA1_CD39_NTPase.
DR PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR PANTHER; PTHR11782:SF81; APYRASE; 1.
DR Pfam; PF01150; GDA1_CD39; 1.
DR PROSITE; PS01238; GDA1_CD39_NTPASE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Hydrolase {ECO:0000256|RuleBase:RU003833};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000015106};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..436
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010837578"
FT ACT_SITE 159
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-1"
FT BINDING 189..193
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-2"
SQ SEQUENCE 436 AA; 47198 MW; F55FB8670F027E5B CRC64;
MAHLVGMMAL LLLLLASSAE IAQARAAAVP PVGKYAVILD AGSTGTRMHV FRFDKRMDLV
KIGDDIEVFA KVNPGLSSYS GRPKEATESI LPLLQKANSV VPQRLMKTTP VKLGATAGLR
LIGDKQAKQI LDAVRGAVHT NTKFQYNPKW INVLEGSQEG SYLWVALNYL LDNLGGDYSK
TVGVIDLGGG SVQMAYAISP ATVVAAPGVP HGKDPYVTKE YLKGRDYNIY VHSYLRYGAL
ASRVEIFKAK EGPFSYCMLR GFSGKYTYNG EEYNATASTG GAQYGKCRGD VMKALKLDAP
CQAKKCTFDG VWNGGGGPGQ ANLYVASSFY YMASQVGLID SDAPSGTSTP MAFRAVAQKI
CRMSLKEVKA KYPKVRDIPY ICMDLVYQYS LLVDGFGLEP TKNITLVEKV KHGEYFIEAA
WPLGEAIEAV APKKGT
//
