ID M8A3K8_TRIUA Unreviewed; 1004 AA.
AC M8A3K8;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=TRIUR3_14743 {ECO:0000313|EMBL:EMS66536.1};
OS Triticum urartu (Red wild einkorn) (Crithodium urartu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4572 {ECO:0000313|EMBL:EMS66536.1};
RN [1] {ECO:0000313|EMBL:EMS66536.1, ECO:0000313|Proteomes:UP000015106}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. G1812 {ECO:0000313|Proteomes:UP000015106};
RX PubMed=23535596; DOI=10.1038/nature11997;
RA Ling H.Q., Zhao S., Liu D., Wang J., Sun H., Zhang C., Fan H., Li D.,
RA Dong L., Tao Y., Gao C., Wu H., Li Y., Cui Y., Guo X., Zheng S., Wang B.,
RA Yu K., Liang Q., Yang W., Lou X., Chen J., Feng M., Jian J., Zhang X.,
RA Luo G., Jiang Y., Liu J., Wang Z., Sha Y., Zhang B., Wu H., Tang D.,
RA Shen Q., Xue P., Zou S., Wang X., Liu X., Wang F., Yang Y., An X., Dong Z.,
RA Zhang K., Zhang X., Luo M.C., Dvorak J., Tong Y., Wang J., Yang H., Li Z.,
RA Wang D., Zhang A., Wang J.;
RT "Draft genome of the wheat A-genome progenitor Triticum urartu.";
RL Nature 496:87-90(2013).
RN [2] {ECO:0000313|EnsemblPlants:TuG1812S0000385800.01.T01.s_cds19028}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2022) to UniProtKB.
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DR EMBL; KD030548; EMS66536.1; -; Genomic_DNA.
DR AlphaFoldDB; M8A3K8; -.
DR STRING; 4572.M8A3K8; -.
DR EnsemblPlants; TuG1812S0000385800.01.T01; TuG1812S0000385800.01.T01.s_cds19028; TuG1812S0000385800.01.
DR Gramene; TuG1812S0000385800.01.T01; TuG1812S0000385800.01.T01.s_cds19028; TuG1812S0000385800.01.
DR eggNOG; ENOG502QRJR; Eukaryota.
DR OMA; VRVENCT; -.
DR OrthoDB; 357813at2759; -.
DR Proteomes; UP000015106; Unassembled WGS sequence.
DR ExpressionAtlas; M8A3K8; differential.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR32472:SF11; DISEASE RESISTANCE PROTEIN (TIR-NBS CLASS); 1.
DR PANTHER; PTHR32472; DNA REPAIR PROTEIN RADA; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13676; TIR_2; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015106}.
FT DOMAIN 171..319
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 123..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1004 AA; 113766 MW; 198768241DB76FB1 CRC64;
MELQEESSDV GALVSAPSRN LSSSSSTFVS ANQSPFFTPR SLSARRPEHA HVQHNNSPTG
IALKIGDILS TDTLVQQGQL PSANIRLLLD DASPPPSLCT SSNFGTPAIV YNNPSFISTF
NGPYQGSSSA TPTSNCDRST RKEKQKRQVG VYRKSSSSQP TPSAASVSRL RTYDVYIGFH
GRKASLLRFT NWLRAELEIH GISCFASDRA RCRNSHSHDA VERVMNASTY GIVILTKKSF
GNPYTIEELR NFFGKKNLIP IFFDLSAADC LARDIIEKRG ELWEKHGGEL WMLYGGMENE
WRESVDALSR VVDLQLEAND TNWRASILQA VILLATKLGR RSVVDRVNRW RVRVEKDEFP
FPRNGDFVGR KKELSELELI LFGDVSGEGE KKYFELKTKH RRKGPVSGWS ANNYEQLNAD
TIKGKEPVLW KETEEGIEMQ RLGTPLQHGR QPRVKNGGRY GRKKKTRKIL YGKGIACISG
ESGMGKTDLA LEYAYRFSQR YKMILWVRGE SRYIRHNYLS LRTHLEVDLS VDTRLHEKGS
DRCFEEQEEE AIAKIRQELM RDIPYLVIID NLESEKDWWD KRVIMDLLPQ FGGETHFIIT
TRLPRVMNLE PMKLSYLSGA EAMTLMKGAV KEYPLMEIDA LKVIEEKLGR LTLGLGIVGA
ILSELPITPS RLLDTLNRPS PIRDFSWNDR EVISLKNHEI LVRLLDVCLS IFEHADGPRS
LAIRMVQVSG WFAPSAVPIH MLALAAHKIP KKHRRGPRWR KWWRTLTCGL ATSRMQRSEA
EAAAMLMRFG IARCSAKSEY IQFHDMIRLY ARKRGGTRTA QAAVQSVYLR GSIKHSSEHL
WAACFMAFGF GSDPFLVELR PSELMFFVKQ IVVPLAINTF ITYSRCNAAL ELLRLCTDAL
ERAAESMLSH AGKWRETSIS CFRPVQSEAQ YTYLWQELAL LKASVLETRA KLMLRGGQYG
IGDDLIRKAI FIRTSICGEH HPDTVSARET LSKLTRLLTN VHLS
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