ID M8A8Q7_TRIUA Unreviewed; 804 AA.
AC M8A8Q7;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Phospholipase D {ECO:0000256|PIRNR:PIRNR036470};
DE EC=3.1.4.4 {ECO:0000256|PIRNR:PIRNR036470};
GN ORFNames=TRIUR3_10079 {ECO:0000313|EMBL:EMS68436.1};
OS Triticum urartu (Red wild einkorn) (Crithodium urartu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4572 {ECO:0000313|EMBL:EMS68436.1};
RN [1] {ECO:0000313|EMBL:EMS68436.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23535596; DOI=10.1038/nature11997;
RA Ling H.Q., Zhao S., Liu D., Wang J., Sun H., Zhang C., Fan H., Li D.,
RA Dong L., Tao Y., Gao C., Wu H., Li Y., Cui Y., Guo X., Zheng S., Wang B.,
RA Yu K., Liang Q., Yang W., Lou X., Chen J., Feng M., Jian J., Zhang X.,
RA Luo G., Jiang Y., Liu J., Wang Z., Sha Y., Zhang B., Wu H., Tang D.,
RA Shen Q., Xue P., Zou S., Wang X., Liu X., Wang F., Yang Y., An X., Dong Z.,
RA Zhang K., Zhang X., Luo M.C., Dvorak J., Tong Y., Wang J., Yang H., Li Z.,
RA Wang D., Zhang A., Wang J.;
RT "Draft genome of the wheat A-genome progenitor Triticum urartu.";
RL Nature 496:87-90(2013).
CC -!- FUNCTION: Hydrolyzes glycerol-phospholipids at the terminal
CC phosphodiesteric bond. {ECO:0000256|PIRNR:PIRNR036470}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-
CC sn-glycero-3-phosphate + choline + H(+); Xref=Rhea:RHEA:14445,
CC ChEBI:CHEBI:15354, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57643, ChEBI:CHEBI:58608; EC=3.1.4.4;
CC Evidence={ECO:0000256|PIRNR:PIRNR036470};
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|PIRNR:PIRNR036470};
CC -!- SIMILARITY: Belongs to the phospholipase D family. C2-PLD subfamily.
CC {ECO:0000256|PIRNR:PIRNR036470}.
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DR EMBL; KD006179; EMS68436.1; -; Genomic_DNA.
DR AlphaFoldDB; M8A8Q7; -.
DR STRING; 4572.M8A8Q7; -.
DR eggNOG; KOG1329; Eukaryota.
DR OMA; GQAHNND; -.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0070290; F:N-acylphosphatidylethanolamine-specific phospholipase D activity; IEA:UniProtKB-EC.
DR GO; GO:0004630; F:phospholipase D activity; IEA:UniProtKB-EC.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR024632; PLipase_D_C.
DR InterPro; IPR015679; PLipase_D_fam.
DR InterPro; IPR011402; PLipase_D_pln.
DR PANTHER; PTHR18896; PHOSPHOLIPASE D; 1.
DR PANTHER; PTHR18896:SF59; PHOSPHOLIPASE D ALPHA 2; 1.
DR Pfam; PF12357; PLD_C; 1.
DR PIRSF; PIRSF036470; PLD_plant; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50004; C2; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|PIRNR:PIRNR036470};
KW Hydrolase {ECO:0000256|PIRNR:PIRNR036470};
KW Lipid degradation {ECO:0000256|PIRNR:PIRNR036470};
KW Lipid metabolism {ECO:0000256|PIRNR:PIRNR036470}.
SQ SEQUENCE 804 AA; 89478 MW; A59A63C5287660A7 CRC64;
MAHLRLHGTI NATILGADNI HDRSRHTGIV PSFLGNIVQG VQETTSLGKG LSRMYAAIYL
GSACIARTRT IAVPAAGSAR WNEPLRAYCA HHAADVVISV MIEQLGLNDD TVLGRAYLPA
RELLNANGTT IDRWFDVLGT DRNKLPDGPK IHVQISFRDV ADQGLAWGGG VGDGVVPHTF
FSQRPGCRVT LYQDAHASAE FDPKIRLDGG GLYKPGRCWE DIYDAISNAR HLVYITAWSM
FPHITLVRER DGRQETLGEL LKRKAGEGVQ VLLLVWNDIS SIDGLHEVGV MDTRDQLTAK
YFRGSRVQCV LCPRNWSVRG YILDAKTPVD TVVYSHHQKA ITVDQELPAS SGTLGTGQAH
NNDFSQINFS DEAATLDKGG PRTPWHDIHA KVEGAAAWDV LHNFEQRWSK QGGGKEHLVD
LVALEGKVAP SSWPVTLPGD QEAWNVQLFR SIDSISTVGF PDSMEDAYEA GLIQDKHRVF
ERSIQDAYIH AIRAANSFIY IENQYFAGSS FQWKTHDGID PADVGACQQI PRELSLKIVS
KIEAGERFAV YVVVPMWSEG TPTGRYRQAM LDNQRRTMAL MYDDIAVALQ AKKIDADPRD
YLTFFCLGNR EAKSEGEHLP AKHPKDGTDY ARAQKARRFM IYVHSKMMID QLTKYLRSVD
DEYIVVGSAN LNERSMAGDR DSEIAIGAFQ PHRVNTDAEL AKGHVHGFRM SLWHEHLGKT
HDDFLRPGSL ECVRRVNKMA DEYWNLYVGD QQLTDDLPGH LLTYPVAVSK AGTVSTLKGF
EFFPDTKAPV LGKPTGINDY FMSI
//
