ID   M8DE72_9BACL            Unreviewed;       421 AA.
AC   M8DE72;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=Cytosine deaminase {ECO:0000313|EMBL:EMT51697.1};
DE            EC=3.5.4.1 {ECO:0000313|EMBL:EMT51697.1};
GN   ORFNames=I532_15181 {ECO:0000313|EMBL:EMT51697.1};
OS   Brevibacillus borstelensis AK1.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX   NCBI_TaxID=1300222 {ECO:0000313|EMBL:EMT51697.1, ECO:0000313|Proteomes:UP000012081};
RN   [1] {ECO:0000313|EMBL:EMT51697.1, ECO:0000313|Proteomes:UP000012081}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AK1 {ECO:0000313|EMBL:EMT51697.1,
RC   ECO:0000313|Proteomes:UP000012081};
RA   Rajan I., PoliReddy D., Sugumar T., Rathinam K., Alqarawi S., Khalil A.B.,
RA   Sivakumar N.;
RT   "Assembly of a new bacterial strain Brevibacillus borstelensis AK1.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMT51697.1}.
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DR   EMBL; APBN01000006; EMT51697.1; -; Genomic_DNA.
DR   RefSeq; WP_003389266.1; NZ_APBN01000006.1.
DR   AlphaFoldDB; M8DE72; -.
DR   STRING; 1300222.I532_15181; -.
DR   GeneID; 72736114; -.
DR   PATRIC; fig|1300222.3.peg.3175; -.
DR   OrthoDB; 9815027at2; -.
DR   Proteomes; UP000012081; Unassembled WGS sequence.
DR   GO; GO:0102480; F:5-fluorocytosine deaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004131; F:cytosine deaminase activity; IEA:UniProtKB-EC.
DR   CDD; cd01293; Bact_CD; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR   InterPro; IPR013108; Amidohydro_3.
DR   InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR32027; CYTOSINE DEAMINASE; 1.
DR   PANTHER; PTHR32027:SF0; CYTOSINE DEAMINASE; 1.
DR   Pfam; PF07969; Amidohydro_3; 1.
DR   SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:EMT51697.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000012081}.
FT   DOMAIN          37..398
FT                   /note="Amidohydrolase 3"
FT                   /evidence="ECO:0000259|Pfam:PF07969"
SQ   SEQUENCE   421 AA;  47084 MW;  EECFA78C068DB74D CRC64;
     MLITNAKLRG REGLWQIAIR DGKIVKIATE ITGFEGKVVD AGGALVLPPF IEPHIHLDTT
     LTAGEPSWNV SGTLFEGIQR WSERKQTLTK EDVKERAKTA LKWQVAQGIQ HVRTHVDVTD
     PSLTALHAML EVKEEMAPYV NLQLVAFPQE GILSYANGAE LLEESLRLGA DVVGGIPHYE
     FTREYGVESM RLAFGLAEKY DRLVDIHCDE IDDEQSRFVE VVAAEALRLG IGEKVTASHT
     TAMHSYNDAY ASKLFRLLKL SGINFVANPL VNIHLQGRFD SYPKRRGITR VKEMVQEGIN
     VCFGHDDIFD PWYPLGTGNM LQVLFMGIHA CQLMGYEQIV DSIDLITVNS AKTLHIEAEY
     GIEEGKPGNL IILNAQDEYD AIRRQATVRY SIRHGKIIAE TEPSQPVLRF GDTSEIVTFK
     K
//