ID M8E0D1_9BACI Unreviewed; 91 AA.
AC M8E0D1;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Cell division protein ZapA {ECO:0000256|ARBA:ARBA00015195, ECO:0000256|HAMAP-Rule:MF_02013};
DE AltName: Full=Z ring-associated protein ZapA {ECO:0000256|ARBA:ARBA00033158, ECO:0000256|HAMAP-Rule:MF_02013};
GN Name=zapA {ECO:0000256|HAMAP-Rule:MF_02013};
GN ORFNames=H919_05864 {ECO:0000313|EMBL:EMT46419.1};
OS Anoxybacillus flavithermus AK1.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Anoxybacillus.
OX NCBI_TaxID=1297581 {ECO:0000313|EMBL:EMT46419.1, ECO:0000313|Proteomes:UP000012085};
RN [1] {ECO:0000313|EMBL:EMT46419.1, ECO:0000313|Proteomes:UP000012085}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK1 {ECO:0000313|EMBL:EMT46419.1,
RC ECO:0000313|Proteomes:UP000012085};
RA Rajan I., PoliReddy D., Sugumar T., Rathinam K., Alqarawi S., Khalil A.B.,
RA Sivakumar N.;
RT "Assembly of a new bacterial strain Anoxybacillus flavithermus AK1.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EMT46419.1, ECO:0000313|Proteomes:UP000012085}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK1 {ECO:0000313|EMBL:EMT46419.1,
RC ECO:0000313|Proteomes:UP000012085};
RX PubMed=26044438;
RA Khalil A., Sivakumar N., Qarawi S.;
RT "Genome Sequence of Anoxybacillus flavithermus Strain AK1, a Thermophile
RT Isolated from a Hot Spring in Saudi Arabia.";
RL Genome Announc. 3:e00604-15(2015).
CC -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC GTPase activity, therefore promoting FtsZ assembly into bundles of
CC protofilaments necessary for the formation of the division Z ring. It
CC is recruited early at mid-cell but it is not essential for cell
CC division. {ECO:0000256|ARBA:ARBA00024910, ECO:0000256|HAMAP-
CC Rule:MF_02013}.
CC -!- SUBUNIT: Homodimer. Interacts with FtsZ.
CC {ECO:0000256|ARBA:ARBA00026068, ECO:0000256|HAMAP-Rule:MF_02013}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_02013}.
CC Note=Localizes at mid-cell. In sporulating cells, localizes near the
CC cell poles. {ECO:0000256|HAMAP-Rule:MF_02013}.
CC -!- SIMILARITY: Belongs to the ZapA family. Type 2 subfamily.
CC {ECO:0000256|HAMAP-Rule:MF_02013}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMT46419.1}.
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DR EMBL; APCD01000005; EMT46419.1; -; Genomic_DNA.
DR RefSeq; WP_003396526.1; NZ_APCD01000005.1.
DR AlphaFoldDB; M8E0D1; -.
DR PATRIC; fig|1297581.3.peg.1203; -.
DR Proteomes; UP000012085; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR Gene3D; 6.10.250.790; -; 1.
DR HAMAP; MF_02013; ZapA_type2; 1.
DR InterPro; IPR007838; Cell_div_ZapA-like.
DR InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR InterPro; IPR023688; Cell_div_ZapA_firmicutes.
DR PANTHER; PTHR34981; CELL DIVISION PROTEIN ZAPA; 1.
DR PANTHER; PTHR34981:SF1; CELL DIVISION PROTEIN ZAPA; 1.
DR Pfam; PF05164; ZapA; 1.
DR SUPFAM; SSF102829; Cell division protein ZapA-like; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|HAMAP-
KW Rule:MF_02013};
KW Cell division {ECO:0000256|ARBA:ARBA00022618, ECO:0000256|HAMAP-
KW Rule:MF_02013}; Coiled coil {ECO:0000256|HAMAP-Rule:MF_02013};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_02013};
KW Septation {ECO:0000256|ARBA:ARBA00023210, ECO:0000256|HAMAP-Rule:MF_02013}.
FT COILED 64..91
FT /evidence="ECO:0000256|HAMAP-Rule:MF_02013"
SQ SEQUENCE 91 AA; 10496 MW; 5E2A2E37CEF186AE CRC64;
MKDQHKTRIT VDIYGQQYSI VGTESSSHIR LVASIVDDKM REISAKNPTL DTSKLAVLTA
VNIVHEYIKL KDEYERLLRK MNKEKDDDSD D
//
