ID M9V9I2_MACMU Unreviewed; 192 AA.
AC M9V9I2;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AGJ74700.1};
DE Flags: Fragment;
GN Name=MAMU-DPA {ECO:0000313|EMBL:AGJ74700.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:AGJ74700.1};
RN [1] {ECO:0000313|EMBL:AGJ74700.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24042461; DOI=10.1007/s00251-013-0736-3;
RA Deng Q., Zhang H., Xiang R., Zhang Z., Ling F., Zhuo M., Du H., Wang X.;
RT "Identification of Mamu-DPA1, Mamu-DQA1, and Mamu-DRA alleles in a cohort
RT of Chinese rhesus macaques.";
RL Immunogenetics 65:901-904(2013).
CC -!- SIMILARITY: Belongs to the MHC class II family.
CC {ECO:0000256|RuleBase:RU004238}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KC428043; AGJ74700.1; -; mRNA.
DR AlphaFoldDB; M9V9I2; -.
DR GO; GO:0042613; C:MHC class II protein complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR GO; GO:0002504; P:antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; IEA:UniProtKB-KW.
DR CDD; cd05767; IgC1_MHC_II_alpha; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR014745; MHC_II_a/b_N.
DR InterPro; IPR001003; MHC_II_a_N.
DR PANTHER; PTHR19944:SF64; HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DP ALPHA 1 CHAIN; 1.
DR PANTHER; PTHR19944; MHC CLASS II-RELATED; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF00993; MHC_II_alpha; 1.
DR SMART; SM00407; IGc1; 1.
DR SMART; SM00920; MHC_II_alpha; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS00290; IG_MHC; 1.
PE 2: Evidence at transcript level;
KW Adaptive immunity {ECO:0000256|ARBA:ARBA00023130};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW MHC II {ECO:0000256|ARBA:ARBA00023182};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 96..176
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AGJ74700.1"
FT NON_TER 192
FT /evidence="ECO:0000313|EMBL:AGJ74700.1"
SQ SEQUENCE 192 AA; 22034 MW; 346FE4103A226BF6 CRC64;
LLSLRGAGAI KADHVSTYAM FVQTHRPTGE FMFEFDEDEM FYVDLDKKET VWHLEEFGQA
ISFEAQGGLA NIAILNHNLN ITIQRSNYTQ AANDPPEVTV FPKEPVELGQ PNTLICHIDK
FFPPVLNVTW LCNGEPVTEG VAESLFLPRT DYSFHKFHYL TFVPSAEDYY DCRVEHWGLD
QPLLKHWEAQ EP
//
