ID M9VTQ7_TACFU Unreviewed; 422 AA.
AC M9VTQ7;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Growth/differentiation factor 9 {ECO:0000256|ARBA:ARBA00017637};
GN Name=gdf-9 {ECO:0000313|EMBL:AGJ83086.1};
OS Tachysurus fulvidraco (Yellow catfish) (Pimelodus fulvidraco).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Bagridae; Tachysurus.
OX NCBI_TaxID=1234273 {ECO:0000313|EMBL:AGJ83086.1};
RN [1] {ECO:0000313|EMBL:AGJ83086.1}
RP NUCLEOTIDE SEQUENCE.
RA Nan X., Zhao Q.;
RT "Molecular Cloning of gdf-9 Gene in Yellow Catfish (Pelteobagrus
RT fulvidraco).";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer or heterodimer (Potential). But, in contrast to
CC other members of this family, cannot be disulfide-linked.
CC {ECO:0000256|ARBA:ARBA00026064}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; JX532106; AGJ83086.1; -; mRNA.
DR AlphaFoldDB; M9VTQ7; -.
DR OrthoDB; 5301288at2759; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd19403; TGF_beta_GDF9; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR015617; Growth_differentiation_fac-9_C.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF19; GROWTH_DIFFERENTIATION FACTOR 9; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 2: Evidence at transcript level;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..422
FT /note="Growth/differentiation factor 9"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004104264"
FT DOMAIN 290..422
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 422 AA; 48579 MW; A806D6090B710C38 CRC64;
MVKRSCAVFY LNALVLVMLG TGVSALSGQH AENLVHHGNI LSPLLKALSD HEPWGIHFPR
TRPDSRYVRF MKRLYKLSTK QERSHEASHL YNTVRLITPR QECLDQCGEF LMQDISYSLN
RVRAQEQLLK SVLLYSLDHN YALSLTSHCY LYMKEQTPSD EHMCLSSPSS QHSVSPISFH
FRVNRASHHK WVEVDVTPFL HPLIQGHKKD IHLLINLTCL DDEPGYHTSR SLVELTHMAP
SLLLYLNDTS EVAYQRGSTN TRLGEIHSNH WGENIQSQLY GSGIQRLKWR DRRNAPNITH
FLKSSTESGP QPKFEHPTED CDLYDFRVSF SQLRLDHWII APSKYNPRYC KGICPRVMGH
IYGSPVHTMV QNIIYEKLDS SMPRPSCVPS EYDPLSVLTI ENDGSIAYKE YEEMIANKCT
CR
//
