ID N0E479_9MICO Unreviewed; 634 AA.
AC N0E479;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Penicillin-binding protein transpeptidase {ECO:0000313|EMBL:CCH70625.1};
GN ORFNames=BN10_620006 {ECO:0000313|EMBL:CCH70625.1};
OS Phycicoccus elongatus Lp2.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Phycicoccus.
OX NCBI_TaxID=1193181 {ECO:0000313|EMBL:CCH70625.1, ECO:0000313|Proteomes:UP000013167};
RN [1] {ECO:0000313|EMBL:CCH70625.1, ECO:0000313|Proteomes:UP000013167}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lp2 {ECO:0000313|EMBL:CCH70625.1,
RC ECO:0000313|Proteomes:UP000013167};
RX PubMed=23178666; DOI=10.1038/ismej.2012.136;
RA Kristiansen R., Nguyen H.T.T., Saunders A.M., Nielsen J.L., Wimmer R.,
RA Le V.Q., McIlroy S.J., Petrovski S., Seviour R.J., Calteau A.,
RA Nielsen K.L., Nielsen P.H.;
RT "A metabolic model for members of the genus Tetrasphaera involved in
RT enhanced biological phosphorus removal.";
RL ISME J. 7:543-554(2013).
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCH70625.1}.
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DR EMBL; CAIZ01000133; CCH70625.1; -; Genomic_DNA.
DR RefSeq; WP_010850468.1; NZ_HF570956.1.
DR AlphaFoldDB; N0E479; -.
DR STRING; 1193181.BN10_620006; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_025328_0_0_11; -.
DR OrthoDB; 5241017at2; -.
DR Proteomes; UP000013167; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000013167}.
FT DOMAIN 151..310
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 349..624
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 634 AA; 64261 MW; 23AEA89D858808EA CRC64;
MRSRPALLAS LIAVALVAVV GTVGWRWYST ERDREAGSKS ALAAYVKGWN TKTMTGVSFD
TAGVAEDFTK TVAGMATAPV SANAESLARD GQTATARLTV DWTLPGDRHW KYALPVSLAE
RGGHWVVLAP EGGSRWSPDL PEGASLSIKT VQAKRGDLLD RGGAALMPMS SVYPVQIDPV
RATPESAAGL EGVTGEPAGS LVAKLAAAKA SGSAAPIPVI TYRQADFDAR KAALDALVGV
IYPRSEAPLA PTRTFGQPLL GTYGAVTADL VTASKGRYAA GDRAGLSGLQ LQYDQTLAGK
PGLQVVASTG KVLFEEAAVD GEDVGTTLSV AVQDAAEKAL VAGGSVPSAI VAIDVATGEV
VAAANSPGDG MNRALTGHYA PGSGFKVAST MALLEKGLVT PETVVDCPPT ITVDGKSFRN
FEGGEATGVT FARDFALSCN TAFIGLSGTL APGDLAASGK ALGIGAGWTD RIGVTGTFEG
SIPETTPGTD LAASVIGQGR IEVSPLSMAV AAGSMARGAF LAPTLVKVGA GATTPAPAAL
PQPALDQTRA LMRSVVTEGS GTALQGAPGG DVFGKTGTAE YGTEVPPKTR AWFVGYQGDL
AFAVLVEDGR SGGSVAAPIA RSFLDLYRAA PTAE
//
