ID   N1P8A8_YEASC            Unreviewed;      1301 AA.
AC   N1P8A8;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   RecName: Full=Nuclear mRNA export factor {ECO:0000256|PIRNR:PIRNR037320};
GN   ORFNames=CENPK1137D_3980 {ECO:0000313|EMBL:EIW11362.1};
OS   Saccharomyces cerevisiae (strain CEN.PK113-7D) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=889517 {ECO:0000313|EMBL:EIW11362.1};
RN   [1] {ECO:0000313|EMBL:EIW11362.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CEN.PK113-7D {ECO:0000313|EMBL:EIW11362.1};
RA   Nijkamp J.F., van den Broek M.A., Datema E., de Kok S., Bosman L.,
RA   Luttink M.A., Daran-Lapujade P., Vongsangnak W., Nielsen J., Heijne W.H.M.,
RA   Klaassen P., Platt D., Paddon C.J., Koetter P., van Ham R.C.,
RA   Reinders M.J.T., Pronk J.T., de Ridder D., Daran J.-M.;
RT   "De novo sequencing, assembly and analysis of the genome of the laboratory
RT   strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial
RT   biotechnology.";
RL   Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus envelope {ECO:0000256|PIRNR:PIRNR037320}.
CC   -!- SIMILARITY: Belongs to the SAC3 family. {ECO:0000256|ARBA:ARBA00038443,
CC       ECO:0000256|PIRNR:PIRNR037320}.
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DR   EMBL; CM001525; EIW11362.1; -; Genomic_DNA.
DR   HOGENOM; CLU_006094_0_0_1; -.
DR   Proteomes; UP000013192; Chromosome IV.
DR   GO; GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.
DR   GO; GO:0070390; C:transcription export complex 2; IEA:UniProtKB-UniRule.
DR   GO; GO:0006406; P:mRNA export from nucleus; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:UniProt.
DR   GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.25.40.990; -; 1.
DR   Gene3D; 6.10.250.2880; -; 1.
DR   InterPro; IPR000717; PCI_dom.
DR   InterPro; IPR017173; Sac3.
DR   InterPro; IPR045107; SAC3/GANP/THP3.
DR   InterPro; IPR005062; SAC3/GANP/THP3_conserved.
DR   InterPro; IPR024293; SAC3_helical.
DR   PANTHER; PTHR12436; 80 KDA MCM3-ASSOCIATED PROTEIN; 1.
DR   PANTHER; PTHR12436:SF3; GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN; 1.
DR   Pfam; PF12209; SAC3; 1.
DR   Pfam; PF03399; SAC3_GANP; 1.
DR   PIRSF; PIRSF037320; mRNA_export_factor_Sac3; 1.
DR   PROSITE; PS50250; PCI; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|PIRNR:PIRNR037320}.
FT   DOMAIN          333..524
FT                   /note="PCI"
FT                   /evidence="ECO:0000259|PROSITE:PS50250"
FT   REGION          54..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          591..626
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          689..715
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1164..1185
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          147..177
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        54..74
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        691..715
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1301 AA;  149561 MW;  2CE9423B4D02932A CRC64;
     MNTSFGSVVP STNFNFFKGH GNNDNTSANS TVNNSNFFLN SNETKPSKNV FMVHSTSQKK
     SQQPLQNLSH SPSYTENKPD KKKKYMINDA KTIQLVGPLI SSPDNLGFQK RSHKARELPR
     FLINQEPQLE KRAFVQDPWD KANQEKMISL EESIDDLNEL YETLKKMRNT ERSIMEEKGL
     VDKADSAKDL YDAIVFQGTC LDMCPTFERS RRNVEYTVYS YEKNQPNDKK ASRTKALKVF
     ARPAAAAAPP LPSDVRPPHI LVKTLDYIVD NLLTTLPESE GFLWDRMRSI RQDFTYQNYS
     GPEAVDCNER IVRIHLLILH IMVKSNVEFS LQQELEQLHK SLITLSEIYD DVRSSGGTCP
     NEAEFRAYAL LSKIRDPQYD ENIQRLPKHI FQDKLVQMAL CFRRVISNSA YTERGFVKTE
     NCLNFYARFF QLMQSPSLPL LMGFFLQMHL TDIRFYALRA LSHTLNKKHK PIPFIYLENM
     LLFNNRQEII EFCNYYSIEI INGDAADLKT LQHYSHKLSE TQPLKKTYLT CLERRLQKTT
     YKGLINGGGD NLASSVYVKD PKKDRIPSIA DQSFLMENFQ NNYNEKLNQN SSVKPQINTS
     PKRVATRPNH FPFSQESKQL PQISQSQTLS TNPLLTPQVH GDLSEQKQQQ IKTVTDGGSP
     FVFDQSAQNS TVQASKAHMI STTSNGAYDE KLSSEQEEMR KKEEQRIEEE KTQLKKKQEN
     ADKQVITEQI ANDLIKEVVN SSVVSIVKRE FSEANYRKDF IDTMTRELYD AFLHERLYLI
     YMDSRAELKR NSTLKKKFFE KWQASYSQTK KNRILEEKKR EEIKLVSHQL GVPGFKKSTC
     LFRTPYKGNV NSSFMLSSSD KNLIFSPVND EFNKFATHLT KISKLWQPLE MRSIYYDNLT
     KKFPSNSLTP ANLFIYAKDW TSLSNRWILS KFNLQTAQDS KKFSNNIISS RVICIDDEYE
     PSDFSDLQLL IFNTGVTNPD IFDLEMKLKD DGEELIKLIT GISLNTNICF SLLIIYWESA
     ENTLSESTIK HLLKLNRISK NYSSVIERID LMNLTEESPH KCLEDKLSEI SHSYVYKLTE
     RGKYDKTLRQ KRSLAGIHSR STQLQTTKDI DQKMKKMLEK EKNKYQQQID ERNTYAHLES
     HIDASPRSKK RKLPILLSTS HSSQFKTPLA SRLNTSGSST SPPLPSHLAM KFRKNSRVTS
     LHTVLPVSTP SHSNNIPAAS FSGNNTTDIQ SQQLIENQKS TSVYLNNVSE RILGNQEICQ
     TPINPVTPVL DGADQGKEDI PDSILELKIL IDSVKKKVNN D
//