ID N1QJP0_SPHMS Unreviewed; 824 AA.
AC N1QJP0;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=HECT domain-containing protein {ECO:0000259|PROSITE:PS50237};
GN ORFNames=SEPMUDRAFT_113413 {ECO:0000313|EMBL:EMF17420.1};
OS Sphaerulina musiva (strain SO2202) (Poplar stem canker fungus) (Septoria
OS musiva).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Sphaerulina.
OX NCBI_TaxID=692275 {ECO:0000313|EMBL:EMF17420.1, ECO:0000313|Proteomes:UP000016931};
RN [1] {ECO:0000313|EMBL:EMF17420.1, ECO:0000313|Proteomes:UP000016931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SO2202 {ECO:0000313|EMBL:EMF17420.1,
RC ECO:0000313|Proteomes:UP000016931};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
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DR EMBL; KB456260; EMF17420.1; -; Genomic_DNA.
DR RefSeq; XP_016765541.1; XM_016901028.1.
DR AlphaFoldDB; N1QJP0; -.
DR STRING; 692275.N1QJP0; -.
DR GeneID; 27898165; -.
DR eggNOG; KOG0941; Eukaryota.
DR HOGENOM; CLU_001858_0_0_1; -.
DR OMA; APWIMIN; -.
DR OrthoDB; 1820836at2759; -.
DR Proteomes; UP000016931; Unassembled WGS sequence.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0000209; P:protein polyubiquitination; IEA:InterPro.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 2.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 2.
DR Gene3D; 6.10.130.10; Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain (AZUL); 1.
DR InterPro; IPR032353; AZUL.
DR InterPro; IPR042556; AZUL_sf.
DR InterPro; IPR044611; E3A/B/C-like.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR PANTHER; PTHR45700:SF8; HECT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45700; UBIQUITIN-PROTEIN LIGASE E3C; 1.
DR Pfam; PF16558; AZUL; 1.
DR Pfam; PF00632; HECT; 1.
DR SMART; SM00119; HECTc; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS50237; HECT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016931};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 447..824
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT REGION 236..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 791
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ SEQUENCE 824 AA; 91936 MW; B7D44C5D27014C14 CRC64;
MQMASDEDMD GSVLTARELV ARYEYQLLHG CQHANCTEPL CLTGHSNVSD RAVRKYTARS
AKTVAMALCA GPRPRLHLCR YCVPSPSDPA PPRPASSSPS DLRDPSSLSQ LLSDTQAVQS
FHISGSASDM LELASKHRLL DQLLTPSSRN FWSSRDLPNA LASCLDWLLN LLPNQRPAIW
EMLNCEIISK GSAVPSTVES KPSDSKWNAW VEVLDILDNP AYLRLWERAL RVVGGRMSSG
PGPPENAAGG RTSGDGGDNG AIDMLISHVS SRENDRSHIP LATIVWLKRL FATVWDGNPV
LDRGSVAHVI LELLQSWKHL GTITSRDAFQ MPLIRLRLAD MDLASSWYMW NSASDDTKKK
HILNFQYLFS SETITTCFRA VNLRRMSRAS GSAIKSGEYR HRHNLDRNSD TDQLPPQLQH
QEEHYMLLYV SRSNLLKDTF DQLWQRRKSE LRRPLRVRMG ADELDIGHDL GGVQVEFFNI
VCKHIFSEEA QMFTTDPQTG LSYFTAGSLQ PLYMFELFGL LLALAIYNGI TLPVRLPRVL
YHVLCDVELP QPLAMIEDAW PTLARSLRSL LGEFVEDLEY AFPLEANGLR LSCLHVGNRH
ALLTGGRSEL CIHTASLSSS ACGAMPDITE MEHAWPGWKL TMSTSAAEPQ AVTPEHVEDY
INAYSQWLCF DSVLPQLEAF IHGFRSSALI DSQTLSLLGP SRLQAYVEGM DMLNIHDLKA
AVRYDGYVPT QKYILAFWRV IASWPPEKQK LLLKFVTATE RIPISGASSL TFIIKRAYPE
TLQALPTSST CFGTLMLPRY PSTEIMAEKL SLALKFGAEG FGAG
//
