ID N1S6L2_FUSC4 Unreviewed; 489 AA.
AC N1S6L2;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Sterigmatocystin biosynthesis P450 monooxygenase STCB {ECO:0008006|Google:ProtNLM};
GN ORFNames=FOC4_g10000940 {ECO:0000313|EMBL:EMT74478.1};
OS Fusarium oxysporum f. sp. cubense (strain race 4) (Panama disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=2502994 {ECO:0000313|EMBL:EMT74478.1, ECO:0000313|Proteomes:UP000016929};
RN [1] {ECO:0000313|Proteomes:UP000016929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 4 {ECO:0000313|Proteomes:UP000016929};
RA Fang X., Huang J.;
RT "Genome sequencing and comparative transcriptomics of race 1 and race 4 of
RT banana pathogen: Fusarium oxysporum f. sp. cubense.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000016929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 4 {ECO:0000313|Proteomes:UP000016929};
RX PubMed=24743270;
RA Guo L., Han L., Yang L., Zeng H., Fan D., Zhu Y., Feng Y., Wang G.,
RA Peng C., Jiang X., Zhou D., Ni P., Liang C., Liu L., Wang J., Mao C.,
RA Fang X., Peng M., Huang J.;
RT "Genome and Transcriptome Analysis of the Fungal Pathogen Fusarium
RT oxysporum f. sp. cubense Causing Banana Vascular Wilt Disease.";
RL PLoS ONE 9:E95543-E95543(2014).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR EMBL; KB726209; EMT74478.1; -; Genomic_DNA.
DR AlphaFoldDB; N1S6L2; -.
DR STRING; 1229665.N1S6L2; -.
DR HOGENOM; CLU_001570_14_2_1; -.
DR Proteomes; UP000016929; Unassembled WGS sequence.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd11059; CYP_fungal; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24305; CYTOCHROME P450; 1.
DR PANTHER; PTHR24305:SF96; CYTOCHROME P450 MONOOXYGENASE STCB-RELATED; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU000461};
KW Iron {ECO:0000256|RuleBase:RU000461};
KW Metal-binding {ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000016929}.
SQ SEQUENCE 489 AA; 54168 MW; C3D4DD9F8F3DFC56 CRC64;
MYIANHLSLP LLAGVFLVGT VLYALVNAFK SPLRGLPGPW YTHFTHLVLK RQILAGNRVH
YIHLLHQRYG PVVRVSPGEV AVSDLEAFSK IHKIGSGFLK SAWYDGVVPD REPGIFDMRD
PHQHAARRRL FARAFSVSSL LANWESEIRH KTELAVSNIK RDAQSTGADV FKWWTLMATD
VIAHLSFGES FRMLELGKQT PYIDAVQSAL LVSGIRAELS WVYPILRRLP FPGLKKFLSA
DSVVFEHGSI AVRNMQSAGD GLSKANLFSQ MLAESDSQEK TNLSTSSVQQ EASNLIVAGS
DTTAVTLTYL VWAVLKQPQL QAELEREISE LSDELTFEEL KSAPLLNSVI EETLRLYGAA
PGALPRVVPG KGLDVCGHYI PPGTVVSTQA FTLHRNGNIF DDAQRFNGYR FMDKSTLTAA
QKTAFSPFGA GSRICIGLHL AWMELRLGAA LFFRECRGAT LSPEMTDAMM EMENRFLIAP
KGHKCIVKL
//
