ID   N1UFH8_9LEPT            Unreviewed;       321 AA.
AC   N1UFH8;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=3-beta hydroxysteroid dehydrogenase/isomerase family protein {ECO:0000313|EMBL:EMY14785.1};
GN   ORFNames=LEP1GSC043_0506 {ECO:0000313|EMBL:EMY14785.1};
OS   Leptospira weilii str. Ecochallenge.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=1049986 {ECO:0000313|EMBL:EMY14785.1, ECO:0000313|Proteomes:UP000012249};
RN   [1] {ECO:0000313|EMBL:EMY14785.1, ECO:0000313|Proteomes:UP000012249}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ecochallenge {ECO:0000313|EMBL:EMY14785.1,
RC   ECO:0000313|Proteomes:UP000012249};
RA   Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA   Sanka R., DePew J., Purushe J., Haake D.A., Matsunaga J., Vinetz J.M.,
RA   Sutton G.G., Nierman W.C., Fouts D.E.;
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMY14785.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AHMI02000140; EMY14785.1; -; Genomic_DNA.
DR   AlphaFoldDB; N1UFH8; -.
DR   Proteomes; UP000012249; Unassembled WGS sequence.
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR48079; PROTEIN YEEZ; 1.
DR   PANTHER; PTHR48079:SF6; PROTEIN YEEZ; 1.
DR   Pfam; PF01073; 3Beta_HSD; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Isomerase {ECO:0000313|EMBL:EMY14785.1}.
FT   DOMAIN          5..247
FT                   /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF01073"
SQ   SEQUENCE   321 AA;  35597 MW;  DA4BA25E41ECC95E CRC64;
     MNIFITGASG FVGEAATRIL SKKHTVKAMS RSEKADAIIS MVGGKPVRCE LNSVDSNSLK
     GIDVVIHSAA YVEQWGPFQD FWKVNVDGTA QLLEASRKAG VKRFIFIGTE AALFYGQPMI
     DIDESYPYPK NSPFPYSKTK AEAEKLVLKA NSSEMQTISI RPRFIWGPGD KTVLPVLLKM
     IADGNFSWID GGKALTNTTH IYNLIHSIEL ALTKGQGGKA YFVTDDEVFN FRNFLESLLA
     TQKVAAPNRS IPGWLARFLA RILERVWKLF RIKNEPPLTR FSASIMSRDC TIKIDNAKKD
     LGYSPLLTVR QGLAEMPVLG S
//