ID N1UZH9_9MICC Unreviewed; 878 AA.
AC N1UZH9;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=MMPL family protein {ECO:0000313|EMBL:EMY33194.1};
GN ORFNames=D477_016115 {ECO:0000313|EMBL:EMY33194.1};
OS Arthrobacter crystallopoietes BAB-32.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=1246476 {ECO:0000313|EMBL:EMY33194.1, ECO:0000313|Proteomes:UP000010729};
RN [1] {ECO:0000313|EMBL:EMY33194.1, ECO:0000313|Proteomes:UP000010729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BAB-32 {ECO:0000313|EMBL:EMY33194.1,
RC ECO:0000313|Proteomes:UP000010729};
RX PubMed=23833141;
RA Joshi M.N., Pandit A.S., Sharma A., Pandya R.V., Desai S.M., Saxena A.K.,
RA Bagatharia S.B.;
RT "Draft Genome Sequence of Arthrobacter crystallopoietes Strain BAB-32,
RT Revealing Genes for Bioremediation.";
RL Genome Announc. 1:e00452-13(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMY33194.1}.
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DR EMBL; ANPE02000193; EMY33194.1; -; Genomic_DNA.
DR RefSeq; WP_005271482.1; NZ_ANPE02000193.1.
DR AlphaFoldDB; N1UZH9; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000010729; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 305..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 435..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..527
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 669..688
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 695..721
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 733..752
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 784..804
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 810..829
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 318..460
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 478..498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 159..226
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 878 AA; 91261 MW; 49F44EF4AE1A1918 CRC64;
MASLLYKLGK LAARRRWWFI SAWLAVMVAV GGSVAAFSGT LSNTFSIPGT ESQQVLDELQ
ESLPDAAGGL GTIVFTTDDG GEFSQEQRAA VAQLAADLGE HDAVKSATDP FELQAQLDDA
PELIAGGEAE LEAAAGQLEQ GQAELDAGRA QLEPGKLQLQ AAEDQLAAAK AQAAQAEAAG
QSAMAAQIRA QLEAQRAQLE PQKAQLEAAE AQLDEAERQL RDGRDDYESG VADLEAAKLQ
QQSSEGVRFV SAAGDAAFMQ VQFEKTMMEV AKEDREAVQQ MTEAALVGGL NAEYSKDIVE
DISQLFGAAE IIGIAVAAAV LVIMLGTLIA AGLPLLMAVV GVGVGVGGTI ALSGAVEMSS
ISPVLALMLG LAVGIDYSLF IVNRHRSQLL AGMPLAESIG RATGTSGNAV LFAGLTVIIA
LAALAVPAIP FLTVLGLAGA ATVAVAVVVA LTLTPAMLAV IGKRILSKRA WARAGRSGPA
AAGTASTTAD PASVNDPKRS WGRVVTRSPW LALLAGVALL GVMAVPATEL RLGLPDGSSE
PADSTAYRAY TQLGESFGEG INGPLIVVAD RPGGLEGTEA DERLLELSRE LRALDHVTAA
VPFGTSEDGR TAALQVIPEE GPAAESTEDL VHHLRAEAEA LEASTGVGVS VTGQPAMQID
VSDKLADAMP VYLAIVIGLS LILLLLVFRS ILVPLLATAG FLLSLGASFG AVVAIYQWGW
LDSIFGVHDP GPILSFLPMI LIGVLFGLAM DYQMFLVSGM RESYAHGEEA RAAVVSGFNH
GAKVVTAAAI IMVSVFAGFI FSHLTMVRPI GFALALGVLL DAFVVRMTLI PAAMHLLGKS
VWWLPRWLEK VLPDVDVEGA KLAAAAPQER EPEPVGAR
//
